The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

Abstract Calcium (Ca2+) signalling is of paramount importance to immunity. Regulated
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …

Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in
virtually all metozoan cells and serve a wide variety of functions ranging from gene …

During the past two decades calcium (Ca2+) accumulation in energized mitochondria has
emerged as a biological process of utmost physiological relevance. Mitochondrial Ca2+ …

Summary Mitochondrial Ca 2+(Ca 2+ m) uptake is mediated by an inner membrane Ca 2+
channel called the uniporter. Ca 2+ uptake is driven by the considerable voltage present …

Mitochondrial calcium uniporter (MCU) channel is responsible for Ruthenium Red‐sensitive
mitochondrial calcium uptake. Here, we demonstrate MCU oligomerization by …

Calcium ions (Ca 2+) impact nearly every aspect of cellular life. This review examines the
principles of Ca 2+ signaling, from changes in protein conformations driven by Ca 2+ to the …

In electrically nonexcitable cells, Ca2+ influx is essential for regulating a host of kinetically
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …

Calcium (Ca2+) uptake into the mitochondrial matrix is critically important to cellular function.
As a regulator of matrix Ca2+ levels, this flux influences energy production and can initiate …

The role of mitochondria in cell metabolism and survival is controlled by calcium signals that
are commonly transmitted at the close associations between mitochondria and endoplasmic …