Epstein–Barr virus epidemiology, serology, and genetic variability of LMP-1 oncogene among healthy population: an update

MK Smatti, DW Al-Sadeq, NH Ali, G Pintus… - Frontiers in …, 2018 - frontiersin.org
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent of
infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of …

Epidemiology and role of Helicobacter pylori virulence factors in gastric cancer carcinogenesis

A Sukri, A Hanafiah, N Mohamad Zin, NR Kosai - Apmis, 2020 - Wiley Online Library
Infection with Helicobacter pylori is associated with the development of gastric cancer.
Although the prevalence of gastric cancer has declined throughout years due to …

Metagenomic next-generation sequencing to identify pathogens and cancer in lung biopsy tissue

Y Guo, H Li, H Chen, Z Li, W Ding, J Wang, Y Yin… - …, 2021 - thelancet.com
Background Lung biopsy tissue samples can be used for infection detection and cancer
diagnosis. Metagenomic next-generation sequencing (mNGS) has the potential to further …

Epstein–Barr virus and human herpesvirus-6 reactivation in acute COVID-19 patients

B Brooks, C Tancredi, Y Song, AT Mogus, MLW Huang… - Viruses, 2022 - mdpi.com
Beyond their pulmonary disease, many COVID-19 patients experience a complex
constellation of characteristics, including hyperinflammatory responses, autoimmune …

Evaluation of commercially available fully automated and ELISA-based assays for detecting anti-SARS-CoV-2 neutralizing antibodies

HT Zedan, HM Yassine, DW Al-Sadeq, N Liu… - Scientific reports, 2022 - nature.com
Rapid and accurate measurement of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV2)-specific neutralizing antibodies (nAbs) is paramount for monitoring immunity …

[HTML][HTML] Endogenous retroviruses in multiple sclerosis: A network-based etiopathogenic model

S Censi, RM Costantini, A Granzotto… - Ageing Research …, 2024 - Elsevier
The present perspective article proposes an etiopathological model for multiple sclerosis
pathogenesis and progression associated with the activation of human endogenous …

Diagnostic efficiency of three fully automated serology assays and their correlation with a novel surrogate virus neutralization test in symptomatic and asymptomatic …

S Younes, H Al-Jighefee, F Shurrab, DW Al-Sadeq… - Microorganisms, 2021 - mdpi.com
To support the deployment of serology assays for population screening during the COVID-
19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG …

Evaluation of antibody response in symptomatic and asymptomatic COVID-19 patients and diagnostic assessment of new IgM/IgG ELISA kits

HT Al-Jighefee, HM Yassine, MA Al-Nesf, AA Hssain… - Pathogens, 2021 - mdpi.com
This study aims to study the immune response and evaluate the performances of four new
IgM and five IgG enzyme-linked immunosorbent assay (ELISA) kits for detecting anti-severe …

The role of Epstein-Barr virus in modulating key tumor suppressor genes in associated malignancies: epigenetics, transcriptional, and post-translational modifications

AO Fierti, MB Yakass, EA Okertchiri, SM Adadey… - Biomolecules, 2022 - mdpi.com
Epstein-Barr virus (EBV) is ubiquitous and carried by approximately 90% of the world's adult
population. Several mechanisms and pathways have been proposed as to how EBV …

[HTML][HTML] Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies

HM Yassine, H Al-Jighefee, DW Al-Sadeq… - International journal of …, 2021 - Elsevier
Objectives To evaluate and compare the performances of five commercial ELISA assays
(EDI, AnshLabs, Dia. Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG …