Mesenchymal stem cells: amazing remedies for bone and cartilage defects

P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Injectable alginate hydrogels for cell delivery in tissue engineering

SJ Bidarra, CC Barrias, PL Granja - Acta biomaterialia, 2014 - Elsevier
Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential
for use in biomedical applications. Their extracellular matrix-like features have been key …

Stimuli‐responsive biomaterials: Scaffolds for stem cell control

A Gelmi, CE Schutt - Advanced Healthcare Materials, 2021 - Wiley Online Library
Stem cell fate is closely intertwined with microenvironmental and endogenous cues within
the body. Recapitulating this dynamic environment ex vivo can be achieved through …

Cartilage tissue engineering: molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction

M Demoor, D Ollitrault, T Gomez-Leduc… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Articular cartilage defects are a veritable therapeutic problem because
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …

Tissue engineering of functional articular cartilage: the current status

L Kock, CC Van Donkelaar, K Ito - Cell and tissue research, 2012 - Springer
Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …

Quercetin promotes osteogenic differentiation and antioxidant responses of mouse bone mesenchymal stem cells through activation of the AMPK/SIRT1 signaling …

N Wang, L Wang, J Yang, Z Wang… - Phytotherapy …, 2021 - Wiley Online Library
Decrepitude and apoptosis of bone mesenchymal stem cells (BMSCs) induced by reactive
oxygen species (ROS) lead to inhibited osteogenic differentiation, causing decreased bone …

Revisiting the advances in isolation, characterization and secretome of adipose-derived stromal/stem cells

NK Dubey, VK Mishra, R Dubey, YH Deng… - International journal of …, 2018 - mdpi.com
Adipose-derived stromal/stem cells (ASCs) seems to be a promising regenerative
therapeutic agent due to the minimally invasive approach of their harvest and multi-lineage …

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation

BM Minogue, SM Richardson, LAH Zeef… - Arthritis & …, 2010 - Wiley Online Library
Objective Development of stem cell therapies for regenerating the nucleus pulposus (NP)
are hindered by the lack of specific markers by which to distinguish NP cells from articular …

TGF-β and mesenchymal stromal cells in regenerative medicine, autoimmunity and cancer

V de Araújo Farias, AB Carrillo-Gálvez, F Martin… - Cytokine & Growth …, 2018 - Elsevier
Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …

Dual growth factor delivery from bilayered, biodegradable hydrogel composites for spatially-guided osteochondral tissue repair

S Lu, J Lam, JE Trachtenberg, EJ Lee, H Seyednejad… - Biomaterials, 2014 - Elsevier
The present work investigated the use of biodegradable hydrogel composite scaffolds,
based on the macromer oligo (poly (ethylene glycol) fumarate)(OPF), to deliver growth …