Langerhans cell histiocytosis: NACHO update on progress, chaos, and opportunity on the path to rational cures
K Bielamowicz, P Dimitrion, O Abla, S Bomken… - Cancer, 2024 - Wiley Online Library
Langerhans cell histiocytosis (LCH) is a myeloid neoplastic disorder characterized by
lesions with CD1a‐positive/Langerin (CD207)‐positive histiocytes and inflammatory infiltrate …
lesions with CD1a‐positive/Langerin (CD207)‐positive histiocytes and inflammatory infiltrate …
Phase 2 study using low dose cytarabine for adult patients with newly diagnosed Langerhans cell histiocytosis
L Chang, M Lang, H Lin, H Cai, MH Duan, DB Zhou… - Leukemia, 2024 - nature.com
Langerhans cell histiocytosis (LCH) lacks a standardized first-line therapy. This single-
center, phase 2 prospective study (NCT04121819) enrolled 61 newly diagnosed adult LCH …
center, phase 2 prospective study (NCT04121819) enrolled 61 newly diagnosed adult LCH …
Approach to the Patient: From Endocrinopathy to the Diagnosis of a Histiocytic Disorder
P Makras, D Erickson, CJ Davidge-Pitts… - The Journal of …, 2024 - academic.oup.com
Endocrinopathies are frequently the initial presentation of histiocytic neoplasms, which are
rare hematologic disorders affecting multiple organ systems. Langerhans cell histiocytosis …
rare hematologic disorders affecting multiple organ systems. Langerhans cell histiocytosis …
Clinical characteristics, molecular aberrations, treatments, and outcomes of malignant histiocytosis
Malignant histiocytosis (MH) is an extremely rare neoplasm of the macrophage–dendritic
cell lineage. We report the clinical characteristics, molecular aberrations, treatments, and …
cell lineage. We report the clinical characteristics, molecular aberrations, treatments, and …
Long Term Follow-up of Methotrexate and Cytarabine in Adult Patients with Langerhans Cell Histiocytosis
H Lin, X Cao, L Chang, M Lang, ZZ Liu, M Duan… - Blood, 2024 - Elsevier
Background: Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized
by the proliferation and accumulation of mononuclear phagocytes across diverse tissues …
by the proliferation and accumulation of mononuclear phagocytes across diverse tissues …
[HTML][HTML] Multisystemic recurrent Langerhans cell histiocytosis misdiagnosed with chronic inflammation at the first diagnosis: A case report
ZR Zhang, F Chen, HJ Chen - World Journal of Radiology, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Langerhans cell histiocytosis (LCH) is characterized by diabetes insipidus
and is an uncommon occurrence. Pathological biopsies still have a certain degree of …
and is an uncommon occurrence. Pathological biopsies still have a certain degree of …
Isolated Langerhans cell histiocytosis in the stomach of adults: four-case series and literature review
J Zhao, Y Li, Y Zhang, X Mei, W Liu, Y Li - Journal of Hematopathology, 2024 - Springer
Langerhans cell histiocytosis (LCH) of the stomach is rare. Moreover, it is usually found in
pediatric patients with systemic diseases and may be associated with a poor prognosis …
pediatric patients with systemic diseases and may be associated with a poor prognosis …
A Case of Spontaneous Regression of Adult Multi-system Langerhans Cell Histiocytosis Presenting as Liver Tumor Rupture
S Oshima, S Inano, G Honjo, S Tabata, M Fujimoto… - Internal …, 2024 - jstage.jst.go.jp
Adult multisystem Langerhans cell histiocytosis (MS-LCH) is rare and has a poor prognosis.
A 67-year-old man with MS-LCH presented with a hepatic tumor rupture and multiple …
A 67-year-old man with MS-LCH presented with a hepatic tumor rupture and multiple …
[HTML][HTML] Langerhans Cell Histiocytosis Treatment (PDQ®): Treatment-Health Professional Information [NCI]
L Home, C Care, CC Home - kids.networkofcare.org
Histiocytic diseases in children and adults are caused by an abnormal accumulation of cells
of the mononuclear phagocytic system. This summary discusses only Langerhans cell …
of the mononuclear phagocytic system. This summary discusses only Langerhans cell …