Background eIF2α is a regulatory node that controls protein synthesis initiation by its
phosphorylation or dephosphorylation. General control nonderepressible-2 (GCN2), protein …

Initiation of protein synthesis in eukaryotes is a complex process requiring more than 12
different initiation factors, comprising over 30 polypeptide chains. The functions of many of …

With their categorical requirement for host ribosomes to translate mRNA, viruses provide a
wealth of genetically tractable models to investigate how gene expression is remodeled post …

Abstract eIF2A was the first eukaryotic initiator tRNA carrier discovered but its exact function
has remained enigmatic. Uncharacteristic of translation initiation factors, eIF2A is reported to …

Over 60 countries have integrated wastewater-based epidemiology (WBE) in their COVID-
19 surveillance programs, focusing on wastewater treatment plants (WWTP). In this paper …

The extent to which unconventional forms of antigen presentation drive T cell immunity is
unknown. By convention, CD8 T cells recognize viral peptides, or epitopes, in association …

As positive-sense RNA viruses, the genomes of flaviviruses serve as the template for all
stages of the viral life cycle, including translation, replication, and infectious particle …

Bats are natural hosts of a wide variety of viruses, including adenoviruses. European bats
are known to carry mastadenoviruses categorized as species B (widespread in European …

Tomato ringspot virus (ToRSV, genus Nepovirus, family Secoviridae, order Picornavirales) is
a bipartite positive-strand RNA virus, with each RNA encoding one large polyprotein. ToRSV …

Bats are natural hosts for a wide variety of viruses and could therefore be the reservoir,
source and spillover for several mammalian viruses, including adenoviruses. We examined …