[HTML][HTML] Biosensors as diagnostic tools in clinical applications

C Lino, S Barrias, R Chaves, F Adega… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Nowadays, the development of new technological solutions in the medical field, in particular
biosensors, is a priority and a ground for great scientific and financial investment. From …

Acoustic biosensors and microfluidic devices in the decennium: Principles and applications

MP Nair, AJT Teo, KHH Li - Micromachines, 2021 - mdpi.com
Lab-on-a-chip (LOC) technology has gained primary attention in the past decade, where
label-free biosensors and microfluidic actuation platforms are integrated to realize such LOC …

Sensitive and selective DNA detecting electrochemical sensor via double cleaving CRISPR Cas12a and dual polymerization on hyperbranched rolling circle …

J You, H Park, H Lee, K Jang, J Park, S Na - Biosensors and Bioelectronics, 2023 - Elsevier
Electrochemical sensors are widely used for nucleic acid detection. However, they exhibit
low sensitivity and specificity. To overcome these limitations, DNA amplification method is …

Synergistic enhanced rolling circle amplification based on mutS and radical polymerization for single-point mutation DNA detection

S Lee, J You, I Baek, H Park, K Jang, C Park… - Biosensors and …, 2022 - Elsevier
The detection of nucleic acids in biofluids is essential for changing the paradigm of disease
diagnosis. As there are very few nucleic acids present in human biofluids, a high sensitivity …

A simple and highly sensitive naked-eye analysis of EGFR 19del via CRISPR/Cas12a triggered no-nonspecific nucleic acid amplification

C Feng, W Liang, F Liu, Y Xiong, M Chen… - ACS Synthetic …, 2022 - ACS Publications
The mutation status of epidermal growth factor receptor (EGFR) exon 19 is of great
importance for predicting sensitivity to tyrosine kinase inhibitors (TKIs) in the treatment of …

A DNA based visual and colorimetric aggregation assay for the early growth factor receptor (EGFR) mutation by using unmodified gold nanoparticles

S Ramanathan, SCB Gopinath, MKM Arshad… - Microchimica Acta, 2019 - Springer
A genomic DNA-based colorimetric assay is described for the detection of the early growth
factor receptor (EGFR) mutation, which is the protruding reason for non-small cell lung …

Detection of mutant genes with different types of biosensor methods

X Lu, M Cui, Q Yi - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Mutation is a permanent alteration in the sequence of genomic DNA which its integrity and
stability is crucial for all living organism. Recognition of these mutations gives the …

Recent advances in biosensors and sequencing technologies for the detection of mutations

SY Ouedraogo, X Zhou, H Chen, F Chen, C Ma - Microchemical Journal, 2023 - Elsevier
Mutations are changes in the nucleotide sequence that derive from external factors or errors
during cell division. They are the source of many diseases such as cancers, sickle cell …

Analysis of the uniformization of the QCM mass sensitivity distribution through a dot multiring electrode structure

W Pan, X Huang, Q Chen - Analytical Chemistry, 2021 - ACS Publications
In this paper, to improve the uniformity of the quartz crystal microbalance (QCM) mass
sensitivity distribution, the effect of the size of dot ring electrode and dot double-ring …

An FPGA-accelerated quartz crystal measurement system based on a negative feedback loop with quadrature demodulation

H Ying, X Ding, X Chen - IEEE Transactions on Industrial …, 2023 - ieeexplore.ieee.org
Rapid measurement of the resonant frequency of quartz crystal (QC) devices plays a key
role in applying QC-based dynamic monitoring, such as respiration monitoring and kinetic …