In principle, proton therapy offers a substantial clinical advantage over conventional photon
therapy. This is because of the unique depth-dose characteristics of protons, which can be …

The original rationale for proton therapy was its highly conformal depth‐dose distributions
compared to photons, which allow greater sparing of normal tissues and escalation of tumor …

Purpose Compared with photon radiation (XRT), proton beam radiation therapy (PBRT)
reduces dose to normal tissues, which may lead to better neurocognitive outcomes. We …

Proton beam therapy, the most common form of heavy-particle radiation therapy, is not a
new invention, but it has gained considerable public attention because of the high cost of …

Proton beam therapy is a highly conformal form of radiation therapy, which currently
represents an important therapeutic component in multidisciplinary management in …

Because it spares many normal tissues and reduces the integral dose, proton therapy (PT) is
the preferred tumor irradiation technique for treating childhood cancer. However, to the best …

Background High‐dose chemotherapy (HDC) strategies were developed to avoid
unacceptable neurotoxicity associated with craniospinal irradiation in infants with embryonal …

BACKGROUND AND PURPOSE: Proton radiotherapy has been increasingly utilized to treat
pediatric brain tumors, however, limited information exists regarding radiation necrosis …

BACKGROUND AND PURPOSE: The intracranial volume is commonly used for correcting
regional brain volume measurements for variations in head size. Accurate intracranial …

To understand neurocognitive effects of proton radiation therapy (PRT) in patients with low-
grade glioma, we evaluated 20 patients who received this therapy prospectively and over 5 …