Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances

YJ Surh - … Research/Fundamental and Molecular Mechanisms of …, 1999 - Elsevier
Recently, considerable attention has been focused on identifying naturally occurring
chemopreventive substances capable of inhibiting, retarding, or reversing the multi-stage …

Molecular targets of aspirin and cancer prevention

L Alfonso, G Ai, RC Spitale, GJ Bhat - British journal of cancer, 2014 - nature.com
Salicylates from plant sources have been used for centuries by different cultures to treat a
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …

Molecular mechanisms in C-Phycocyanin induced apoptosis in human chronic myeloid leukemia cell line-K562

J Subhashini, SVK Mahipal, MC Reddy… - Biochemical …, 2004 - Elsevier
C-Phycocyanin (C-PC), the major light harvesting biliprotein from Spirulina platensis is of
greater importance because of its various biological and pharmacological properties. It is a …

Aspirin, salicylates, and cancer

PC Elwood, AM Gallagher, GG Duthie, LAJ Mur… - The Lancet, 2009 - thelancet.com
Evidence from a wide range of sources suggests that individuals taking aspirin and related
non-steroidal anti-inflammatory drugs have reduced risk of large bowel cancer. Work in …

Prodigiosin from the supernatant of Serratia marcescens induces apoptosis in haematopoietic cancer cell lines

B Montaner, S Navarro, M Piqué… - British journal of …, 2000 - Wiley Online Library
The effects of supernatant from the bacterial strain Serratia marcescens 2170 (CS‐2170) on
the viability of different haematopoietic cancer cell lines (Jurkat, NSO, HL‐60 and Ramos) …

Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells

YJ Surh, YJ Hurh, JY Kang, E Lee, G Kong, SJ Lee - Cancer letters, 1999 - Elsevier
Resveratrol, a triphenolic stilbene present in grapes and other plants, has striking
antioxidant and anti-inflammatory activities which have been considered to be responsible …

The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential

JG Mahdi, AJ Mahdi, AJ Mahdi, ID Bowen - Cell proliferation, 2006 - Wiley Online Library
For several millennia, the willow tree and salicin have been associated with salicylic acid,
the key precursor molecule that has contributed to the discovery of acetylsalicylic acid …

CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia

V Mateo, L Lagneaux, D Bron, G Biron, M Armant… - Nature medicine, 1999 - nature.com
Thrombospondin forms a'molecular bridge'between phagocytic and apoptotic cells through
interaction with αvβ3/CD36. We report here that engagement of CD47, a newly described …

Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells

O Fingrut, E Flescher - Leukemia, 2002 - nature.com
Cellular stressors induce various outcomes including inhibition of cell proliferation and cell
death. Sodium salicylate (SA), a plant stress hormone, can suppress the proliferation or …

The NF-κB cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

A Khoshnan, C Tindell, I Laux, D Bae… - The Journal of …, 2000 - journals.aai.org
We explored the role of the NF-κB pathway in the survival of primary human CD4+ T
lymphocytes during CD28 costimulation. Transduction of proliferating CD4+ T cells with a …