Genetically modified swine hold great promise in the fields of agriculture and medicine.
Currently, these swine are being used to optimize production of quality meat, to improve our …

During the past two decades, there have been numerous attempts at using animals in order
to produce recombinant human proteins and monoclonal antibodies. However, it is only …

Outlining the fundamental principles by which all interactions occur, this reference focuses
on harnessing the biochemistry of bioorganic compounds in order to separate them …

The production of recombinant human proteins in the milk of transgenic dairy animals offers
a safe, renewable source of commercially important proteins that cannot be produced as …

Transgenic rabbits provide a useful biological model for the study of the regulation of
mammalian genes. However, transgene integration efficiency has generally been low. Here …

The mammary gland of transgenic livestock can be used as a bioreactor for producing
complex therapeutic proteins. However, the capacity for making a given post-translational …

Human protein C (hPC) is glycosylated at three Asn‐X‐Ser/Thr and one atypical Asn‐X‐Cys
sequons. We have characterized the micro‐and macro‐heterogeneity of plasma‐derived …

Transgenic founder rabbits carrying a gene construct consisting of a 2.5 kb murine whey
acidic protein promoter (mWAP), 7.2 kb of the human clotting factor VIII (hFVIII) cDNA and …

The aim of our study was to compare the hFVIII mRNA expression in different organs,
pathological changes and selected haematological and biochemical blood parameters …

The regulatory elements of genes used to target the tissue-specific expression of
heterologous human proteins have been studied in vitro and in transgenic mice. Hybrid …