The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
Oxidative stress (OS) disrupts the chemical integrity of macromolecules and increases the
risk of neurodegenerative diseases. Fisetin is a flavonoid that exhibits potent antioxidant …
risk of neurodegenerative diseases. Fisetin is a flavonoid that exhibits potent antioxidant …
Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …
has resulted in excessive human exposure and due to the potential neurotoxic effects has …
Natural dietary supplementation of anthocyanins via PI3K/Akt/Nrf2/HO-1 pathways mitigate oxidative stress, neurodegeneration, and memory impairment in a mouse …
Well-established studies have shown an elevated level of reactive oxygen species (ROS)
that induces oxidative stress in the Alzheimer's disease (AD) patient's brain and an animal …
that induces oxidative stress in the Alzheimer's disease (AD) patient's brain and an animal …
Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …
Neuroprotective effect of fisetin against amyloid-beta-induced cognitive/synaptic dysfunction, neuroinflammation, and neurodegeneration in adult mice
Alzheimer's disease (AD) is a devastating and progressive neurodegenerative disease and
is characterized pathologically by the accumulation of amyloid beta (Aβ) and the …
is characterized pathologically by the accumulation of amyloid beta (Aβ) and the …
Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review
V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …
considerable attention due to its neurotoxic effects. The widespread use of products made …
Inflammation and Alzheimer's disease: mechanisms and therapeutic implications by natural products
Alzheimer's disease (AD) is a neurodegenerative disorder with no clear causative event
making the disease difficult to diagnose and treat. The pathological hallmarks of AD include …
making the disease difficult to diagnose and treat. The pathological hallmarks of AD include …
Vanillic acid, a bioactive phenolic compound, counteracts LPS-induced neurotoxicity by regulating c-Jun N-terminal kinase in mouse brain
The receptor for advanced glycation end products (RAGE), a pattern recognition receptor
signaling event, has been associated with several human illnesses, including …
signaling event, has been associated with several human illnesses, including …
Probiotics: a promising generation of heavy metal detoxification
RM Abdel-Megeed - Biological trace element research, 2021 - Springer
Different environmental toxins especially heavy metals exist in soil, water, and air recording
toxic effect on human, animal, and plant. These toxicant elements are widespread in …
toxic effect on human, animal, and plant. These toxicant elements are widespread in …
Anthocyanins improve hippocampus-dependent memory function and prevent neurodegeneration via JNK/Akt/GSK3β signaling in LPS-treated adult mice
Microglia plays a critical role in the brain and protects neuronal cells from toxins. However,
over-activation of microglia leads to deleterious effects. Lipopolysaccharide (LPS) has been …
over-activation of microglia leads to deleterious effects. Lipopolysaccharide (LPS) has been …