Viral diseases like influenza, AIDS, hepatitis, and Ebola cause severe epidemics worldwide.
Along with their resistant strains, new pathogenic viruses continue to be discovered so …

A variety of pathogens, including viruses, bacteria and parasites, target cellular lipid droplets
for their replication. Rotaviruses (RVs) infect the villous epithelium of the small intestine and …

Gastroenteritis is among the leading causes of mortality globally in infants and young
children, with rotavirus (RV) causing~ 258 million episodes of diarrhea and~ 128,000 deaths …

An entirely plasmid-based reverse genetics system for rotaviruses was established very
recently. We improved the reverse genetics system to generate recombinant rotavirus by …

Early during the infection process, rotavirus causes the shutoff of cell protein synthesis, with
the nonstructural viral protein NSP3 playing a vital role in the phenomenon. In this work, we …

The non‐structural protein Pns12 of Rice dwarf virus is one of the early proteins expressed
in cultured insect cells, and it is one of 12 proteins that initiate the formation of the viroplasm …

An in vitro culture system of primary cells from white-backed planthopper, an insect vector of
Southern rice black-streaked dwarf virus (SRBSDV), a fijivirus, was established to study …

Rotavirus (RV) replicates in round-shaped cytoplasmic viral factories, although how they
assemble remains unknown. During RV infection, NSP5 undergoes hyperphosphorylation …

Initiation is the rate-limiting step in protein synthesis and therefore an important target for
regulation. For the initiation of translation of most cellular mRNAs, the cap structure at the …

Rotavirus (RV) replication occurs in cytoplasmic inclusions called viroplasms whose
formation requires the interactions of RV proteins NSP2 and NSP5; however, the specific …