Anti-COVID drugs: repurposing existing drugs or search for new complex entities, strategies and perspectives
A Pawełczyk, L Zaprutko - Future Medicinal Chemistry, 2020 - Taylor & Francis
At the end of 2019, a novel virus causing severe acute respiratory syndrome to spread
globally. There are currently no effective drugs targeting SARS-CoV-2. In this study, based …
globally. There are currently no effective drugs targeting SARS-CoV-2. In this study, based …
Engineered production of bioactive natural products from medicinal plants
Plant natural products have been particularly important due to their use in food, cosmetic,
and pharmaceutical industries. In particular, Traditional Chinese Medicine provides a …
and pharmaceutical industries. In particular, Traditional Chinese Medicine provides a …
Antitussive noscapine and antiviral drug conjugates as arsenal against COVID-19: a comprehensive chemoinformatics analysis
Coronavirus pandemic has caused a vast number of deaths worldwide. Thus creating an
urgent need to develop effective counteragents against novel coronavirus disease (COVID …
urgent need to develop effective counteragents against novel coronavirus disease (COVID …
Bioactivity and in silico studies of isoquinoline and related alkaloids as promising antiviral agents: an insight
Viruses are widely recognized as the primary cause of infectious diseases around the world.
The ongoing global pandemic due to the emergence of SARS-CoV-2 further added fuel to …
The ongoing global pandemic due to the emergence of SARS-CoV-2 further added fuel to …
Volatile molecules for COVID‐19: A possible pharmacological strategy?
C Colalto - Drug Development Research, 2020 - Wiley Online Library
COVID‐19 is a novel coronavirus disease with a higher incidence of bilateral pneumonia
and pleural effusion. The high pulmonary tropism and contagiousness of the virus, severe …
and pleural effusion. The high pulmonary tropism and contagiousness of the virus, severe …
Developing benzylisoquinoline alkaloid-enriched opium poppy via CRISPR-directed genome editing: A review
Z Aghaali, MR Naghavi - BMC Plant Biology, 2024 - Springer
Among plant-derived secondary metabolites are benzylisoquinoline alkaloids (BIAs) that
play a vital role in medicine. The most conspicuous BIAs frequently found in opium poppy …
play a vital role in medicine. The most conspicuous BIAs frequently found in opium poppy …
Lithium as a candidate treatment for COVID‐19: promises and pitfalls
RP Rajkumar - Drug Development Research, 2020 - Wiley Online Library
The pandemic of respiratory illness caused by a novel coronavirus (SARS‐nCoV‐2) is a
global health crisis. Despite numerous preliminary results, there is as yet no treatment of …
global health crisis. Despite numerous preliminary results, there is as yet no treatment of …
Biological and pharmacological activities of noscapine: focusing on its receptors and mechanisms
F Nourbakhsh, VR Askari - BioFactors, 2021 - Wiley Online Library
Noscapine has been mentioned as one of the effective drugs with potential therapeutic
applications. With few side effects and amazing capabilities, noscapine can be considered …
applications. With few side effects and amazing capabilities, noscapine can be considered …
Evaluation of noscapine-licorice combination effects on cough relieving in COVID-19 outpatients: A randomized controlled trial
S Barati, F Feizabadi, H Khalaj… - Frontiers in …, 2023 - frontiersin.org
Background: As February 2023, SARS-CoV-2 is still infecting people and children
worldwide. Cough and dyspnea are annoying symptoms almost present in a large …
worldwide. Cough and dyspnea are annoying symptoms almost present in a large …
Synthesis and modification of noscapine derivatives as promising future anticancer agents
F Nemati, P Salehi - Bioorganic Chemistry, 2024 - Elsevier
Noscapine, a tetrahydroisoquinoline alkaloid, was first isolated from Papaver somniferum
and identified by Rabiquet in 1817. It has been used as an anti-tussive agent since the mid …
and identified by Rabiquet in 1817. It has been used as an anti-tussive agent since the mid …