Recent technological advances in glycobiology and glycochemistry are paving the way for a
new era in carbohydrate vaccine design. This is enabling greater efficiency in the …

The intracellular protozoan Toxoplasma gondii is a widespread opportunistic parasite of
humans and animals. Normally, T. gondii establishes itself within brain and skeletal muscle …

Protozoan infections are a serious global health problem,. Natural killer (NK) cells and
cytolytic T lymphocytes (CTLs) eliminate pathogen-infected cells by releasing cytolytic …

Publisher Summary Among the protozoa of the Trypanosomatidae family, a large number of
species represent agents of diseases, such as Chagas' disease. This chapter reviews some …

Cell invasion by Trypanosoma cruzi and its intracellular replication are essential for
continuation of the parasite life cycle and for production of Chagas' disease. T. cruzi is able …

Host resistance to infection by Trypanosoma cruzi is dependent on both natural and
acquired immune responses. During the first week of infection in mice, NK cell-derived …

Sera of patients with chronic Chagas' disease (American trypanosomiasis) contain elevated
levels of anti-alpha-galactosyl antibodies that are lytic to Trypanosoma cruzi. The T. cruzi …

Gamma interferon (IFN-gamma) plays an important role in experimental Trypanosoma cruzi
infections, presumably by controlling the early replication of parasites in host macrophages …

The intracellular protozoan parasite Trypanosoma cruzi is the causative agent of Chagas'
disease, a serious disorder that affects millions of people in Latin America. Despite the …

Chagas disease (CD) is caused by the infection with the protozoan haemoflagellate
Trypanosoma cruzi. This disease is still a great menace to public health, and is largely …