Temperature-resistant and solvent-tolerant lipases as industrial biocatalysts: Biotechnological approaches and applications

AR Ismail, H Kashtoh, KH Baek - International Journal of Biological …, 2021 - Elsevier
The development of new biocatalytic systems to replace the chemical catalysts, with suitable
characteristics in terms of efficiency, stability under high temperature reactions and in the …

Microbial lipases and their potential in the production of pharmaceutical building blocks

CA Godoy, JS Pardo-Tamayo, O Barbosa - International Journal of …, 2022 - mdpi.com
Processes involving lipases in obtaining active pharmaceutical ingredients (APIs) are crucial
to increase the sustainability of the industry. Despite their lower production cost, microbial …

[图书][B] Food lipids: chemistry, nutrition, and biotechnology

CC Akoh - 2017 - taylorfrancis.com
Maintaining the high standards that made the previous editions such well-respected and
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …

Enzymes in lipid modification

UT Bornscheuer - Annual review of food science and technology, 2018 - annualreviews.org
This article reviews the application of enzymes in lipid modification. Lipases are the most
established biocatalysts used for the synthesis of structured triacylglycerols, fats, and …

Main structural targets for engineering lipase substrate specificity

SH Albayati, M Masomian, SNH Ishak… - Catalysts, 2020 - mdpi.com
Microbial lipases represent one of the most important groups of biotechnological
biocatalysts. However, the high-level production of lipases requires an understanding of the …

[HTML][HTML] An extracellular lipase from Amycolatopsis mediterannei is a cutinase with plastic degrading activity

Y Tan, GT Henehan, GK Kinsella, BJ Ryan - Computational and structural …, 2021 - Elsevier
An extracellular lipase from Amycolatopsis mediteranei (AML) with potential applications in
process biotechnology was recently cloned and examined in this laboratory. In the present …

Engineering and application of enzymes for lipid modification, an update

K Zorn, I Oroz-Guinea, H Brundiek… - Progress in lipid …, 2016 - Elsevier
This review first provides a brief introduction into the most important tools and strategies for
protein engineering (ie directed evolution and rational protein design combined with high …

Alteration of Chain Length Selectivity of Candida antarctica Lipase A by Semi‐Rational Design for the Enrichment of Erucic and Gondoic Fatty Acids

K Zorn, I Oroz‐Guinea, H Brundiek… - … synthesis & catalysis, 2018 - Wiley Online Library
Biotechnological strategies using renewable materials as starting substrates are a promising
alternative to traditional oleochemical processes for the isolation of different fatty acids …

Tuning selectivity in CalA lipase: beyond tunnel engineering

L Alejaldre, C Lemay-St-Denis, JN Pelletier… - Biochemistry, 2022 - ACS Publications
Engineering studies of Candida (Pseudozyma) antarctica lipase A (CalA) have
demonstrated the potential of this enzyme in the selective hydrolysis of fatty acid esters of …

Balancing the stability–activity trade‐off by fine‐tuning dehalogenase access tunnels

V Liskova, D Bednar, T Prudnikova… - …, 2015 - Wiley Online Library
A variant of the haloalkane dehalogenase DhaA with greatly enhanced stability and
tolerance of organic solvents but reduced activity was created by mutating four residues in …