Beyond E-cadherin: roles of other cadherin superfamily members in cancer
F Van Roy - Nature Reviews Cancer, 2014 - nature.com
Abstract Loss of cadherin 1 (CDH1; also known as epithelial cadherin (E-cadherin)) is used
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …
Involvement of members of the cadherin superfamily in cancer
G Berx, F Van Roy - Cold Spring Harbor perspectives in …, 2009 - cshperspectives.cshlp.org
We review the role of cadherins and cadherin-related proteins in human cancer. Cellular
and animal models for human cancer are also dealt with whenever appropriate. E-cadherin …
and animal models for human cancer are also dealt with whenever appropriate. E-cadherin …
Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is among the most common malignancies,
but little is known about its spatial intratumoral heterogeneity (ITH) and temporal clonal …
but little is known about its spatial intratumoral heterogeneity (ITH) and temporal clonal …
[HTML][HTML] Gene methylation in gastric cancer
Y Qu, S Dang, P Hou - Clinica chimica acta, 2013 - Elsevier
Gastric cancer is one of the most common malignancies and remains the second leading
cause of cancer-related death worldwide. Over 70% of new cases and deaths occur in …
cause of cancer-related death worldwide. Over 70% of new cases and deaths occur in …
Hsa_circ_0001666 suppresses the progression of colorectal cancer through the miR‐576‐5p/PCDH10 axis
J Zhou, L Wang, Q Sun, R Chen… - Clinical and …, 2021 - Wiley Online Library
Abstract Background Though circular RNAs, new non‐coding RNA classes have
demonstrated that they have an essential role in the initiation as well as development of …
demonstrated that they have an essential role in the initiation as well as development of …
Protocadherins at the crossroad of signaling pathways
A Pancho, T Aerts, MD Mitsogiannis… - Frontiers in Molecular …, 2020 - frontiersin.org
Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …
Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway
Z Yang, CB Qu, Y Zhang, WF Zhang, DD Wang… - Oncogene, 2019 - nature.com
Abstract p53, circRNAs and miRNAs are important components of the regulatory network
that activates the EMT program in cancer metastasis. In prostate cancer (PCa), however, it …
that activates the EMT program in cancer metastasis. In prostate cancer (PCa), however, it …
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma
Y Liu, L Ouyang, C Mao, Y Chen, T Li, N Liu, Z Wang… - Oncogene, 2022 - nature.com
Liver cancer, a result of multifactorial interplay between heredity and the environment, is one
of the leading causes of cancer-related death worldwide. Hepatocellular carcinoma (HCC) is …
of the leading causes of cancer-related death worldwide. Hepatocellular carcinoma (HCC) is …
Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis
Abstract Purpose: Yes-associated protein 1 (YAP1) is a multifunctional protein that can
interact with different transcription factors to activate gene expression. The role of YAP1 in …
interact with different transcription factors to activate gene expression. The role of YAP1 in …