[HTML][HTML] Recent advances in chemotherapeutics for leishmaniasis: Importance of the cellular biochemistry of the parasite and its molecular interaction with the host

R Singh, M Kashif, P Srivastava, PP Manna - Pathogens, 2023 - mdpi.com
Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …

[HTML][HTML] Metabolic Pathways of Leishmania Parasite: Source of Pertinent Drug Targets and Potent Drug Candidates

S Jain, U Sahu, A Kumar, P Khare - Pharmaceutics, 2022 - mdpi.com
Leishmaniasis is a tropical disease caused by a protozoan parasite Leishmania that is
transmitted via infected female sandflies. At present, leishmaniasis treatment mainly counts …

[PDF][PDF] Dermatological effects of Pistacia species: A systematic review

M Bozorgi, M Iranzad, A Ali… - Journal of Herbmed …, 2024 - herbmedpharmacol.com
Skin medicines and cosmetics can benefit from herbal medicines. Several herbal medicinal
and cosmetic products have been developed in recent years for preventing and treating …

[HTML][HTML] Selene-Ethylenelacticamides and N-Aryl-Propanamides as Broad-Spectrum Leishmanicidal Agents

NF de Sousa, HD da Silva Souza, RPB de Menezes… - Pathogens, 2023 - mdpi.com
The World Health Organization classifies Leishmania as one of the 17 “neglected diseases”
that burden tropical and sub-tropical climate regions with over half a million diagnosed …

[HTML][HTML] Strategies to control human health risks arising from antibiotics in the environment: molecular modification of qns for enhanced plant–microbial synergistic …

P Sun, W Zhao - International Journal of Environmental Research and …, 2021 - mdpi.com
In the present work, a comprehensive screening and evaluation system was established to
improve the plant–microbial synergistic degradation effects of QNs. The study included the …

Evaluation of antitumoral and apoptotic potentials of masticadienonic acid and tirucallol from Pistacia vera L. stems

H Emlik, ID Karagoz, L Yabo-Dambagi… - Plant Biosystems-An …, 2023 - Taylor & Francis
Breast cancer is one of the most common forms of cancer in women, therefore it has become
necessary to find more effective and less toxic drugs to minimize the disadvantages of …

Hydroxycoumarins and some flavonoids from Pistacia atlantica Desf. as multi-targets inhibitors for Alzheimer's disease: Molecular docking and ADMET studies

M Lamrani, T Serseg, K Benarous, I Sifi… - … Computer-Aided Drug …, 2023 - ingentaconnect.com
Objective: The present study aimed to identify new selective inhibitors for
acetylcholinesterase, butyrylcholinesterase, monoacylglycerol lipase, beta-secretase, and …

Role of Natural plant extracts for potential Antileishmanial targets–In-depth review of the molecular mechanism

N Naik, RS Kaushal, TKU Upadhyay… - Cellular and molecular …, 2022 - cellmolbiol.org
A group of protozoan parasites known as Leishmania species can cause a variety of chronic
illnesses, ranging from self-healing lesions to fatal outcomes. Drug-resistant pathogens …

Advances in Antileishmanial Chemotherapy

S Shuhail, S Das, T Datta, P Tyagi, M Tasleem… - … and Solutions Against …, 2024 - Springer
Leishmaniasis, an endemic tropical ailment, has invariably been categorized as one of the
“neglected tropical diseases” and is constantly linked with poverty. However, under current …

[PDF][PDF] In-silico Screening and Identification of Novel Trypanothione Reductase Inhibitor from Leishmania

MM Rafeeq, ZM Sain, KM Amir, N Binothman… - academia.edu
The negative effects of leishmanicidal medications are numerous, and drug resistance to all
of them has been observed. As a result, new medication development and the identification …