Natriuretic peptides, which are activated in heart failure, play an important cardioprotective
role. The most notable of the cardioprotective natriuretic peptides are atrial natriuretic …

Cardiac natriuretic peptides (NPs), atrial NP (ANP) and B-type NP (BNP) are true hormones
produced and released by cardiomyocytes, exerting several systemic effects. Together with …

After its discovery in the early 1980s, the natriuretic peptide (NP) system has been
extensively characterized and its potential influence in the development and progression of …

Natriuretic peptides are a family of structurally related but genetically distinct
hormones/paracrine factors that regulate blood volume, blood pressure, ventricular …

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

C-type natriuretic peptide (CNP) is an autocrine and paracrine mediator released by
endothelial cells, cardiomyocytes and fibroblasts that regulates vital physiological functions …

BACKGROUND Atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type
natriuretic peptide (CNP) are a family of structurally related peptides that participate in the …

B-type natriuretic peptide (BNP), a neurohormone synthesized in the cardiac ventricles, is
released as preproBNP and then enzymatically cleaved to the N-terminal-proBNP (NT …

The discovery in the early 1980s of atrial natriuretic peptide, a circulating peptide with
natriuretic/diuretic and vasorelaxant properties was greeted with excitement since the …

The landmark report by de Bold et al. in 1981 signified the heart as one of the endocrine
organs involved in fluid and salt balance (de Bold AJ, Borenstein HB, Veress AT …