Dissecting malaria biology and epidemiology using population genetics and genomics
Molecular approaches have an increasingly recognized utility in surveillance of malaria
parasite populations, not only in defining prevalence and incidence with higher sensitivity …
parasite populations, not only in defining prevalence and incidence with higher sensitivity …
[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples
A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …
populations to evolve in response to malaria control interventions. The widespread use of …
Whole genome sequencing contributions and challenges in disease reduction focused on malaria
Simple Summary Malaria is one of the most severe life-threatening human vector-borne
diseases worldwide today, leading to high mortality. Children under the age of five and …
diseases worldwide today, leading to high mortality. Children under the age of five and …
THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites
As many malaria-endemic countries move towards elimination of Plasmodium falciparum,
the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology …
the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology …
High Genetic Diversity of Plasmodium falciparum in the Low-Transmission Setting of the Kingdom of Eswatini
Background To better understand transmission dynamics, we characterized Plasmodium
falciparum genetic diversity in Eswatini, where transmission is low and sustained by …
falciparum genetic diversity in Eswatini, where transmission is low and sustained by …
Diversity and Multiplicity of P. falciparum infections among asymptomatic school children in Mbita, Western Kenya
Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important
surrogate indicators for assessing malaria transmission intensity in different regions of …
surrogate indicators for assessing malaria transmission intensity in different regions of …
Multiplication rate variation in the human malaria parasite Plasmodium falciparum
L Murray, LB Stewart, SJ Tarr, AD Ahouidi, M Diakite… - Scientific reports, 2017 - nature.com
It is important to understand intrinsic variation in asexual blood stage multiplication rates of
the most virulent human malaria parasite, Plasmodium falciparum. Here, multiplication rates …
the most virulent human malaria parasite, Plasmodium falciparum. Here, multiplication rates …
Parasite genetic diversity reflects continued residual malaria transmission in Vhembe District, a hotspot in the Limpopo Province of South Africa
Abstract Background South Africa aims to eliminate malaria transmission by 2023. However,
despite sustained vector control efforts and case management interventions, the Vhembe …
despite sustained vector control efforts and case management interventions, the Vhembe …
Selective sweep suggests transcriptional regulation may underlie Plasmodium vivax resilience to malaria control measures in Cambodia
Cambodia, in which both Plasmodium vivax and Plasmodium falciparum are endemic, has
been the focus of numerous malaria-control interventions, resulting in a marked decline in …
been the focus of numerous malaria-control interventions, resulting in a marked decline in …
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
Novel interventions that leverage the heterogeneity of parasite transmission are needed to
achieve malaria elimination. To better understand spatial and temporal dynamics of …
achieve malaria elimination. To better understand spatial and temporal dynamics of …