Nebulised hypertonic saline for cystic fibrosis

P Wark, VM McDonald, S Smith - Cochrane Database of …, 2023 - cochranelibrary.com
Background Hypertonic saline enhances mucociliary clearance and may lessen the
destructive inflammatory process in the airways. This is an update of a previously published …

Devices for improved delivery of nebulized pharmaceutical aerosols to the lungs

W Longest, B Spence, M Hindle - Journal of aerosol medicine and …, 2019 - liebertpub.com
Nebulizers have a number of advantages for the delivery of inhaled pharmaceutical
aerosols, including the use of aqueous formulations and the ability to deliver process …

Hypertonic saline suppresses NADPH oxidase-dependent neutrophil extracellular trap formation and promotes apoptosis

A Nadesalingam, JHK Chen, A Farahvash… - Frontiers in …, 2018 - frontiersin.org
Tonicity of saline (NaCl) is important in regulating cellular functions and homeostasis.
Hypertonic saline is administered to treat many inflammatory diseases, including cystic …

Timing of hypertonic saline inhalation for cystic fibrosis

M Elkins, R Dentice - Cochrane Database of Systematic …, 2020 - cochranelibrary.com
Background Inhalation of hypertonic saline improves sputum rheology, accelerates
mucociliary clearance and improves clinical outcomes of people with cystic fibrosis. This is …

In vitro determination of the main effects in the design of high-flow nasal therapy systems with respect to aerosol performance

G Bennett, M Joyce, L Sweeney, R MacLoughlin - Pulmonary therapy, 2018 - Springer
Introduction The use of concurrent aerosol delivery during high-flow nasal therapy (HFNT)
may be exploited to facilitate the delivery of a variety of prescribed medications for …

Development of a high-flow nasal cannula and pharmaceutical aerosol combination device

BM Spence, W Longest, X Wei, S Dhapare… - Journal of aerosol …, 2019 - liebertpub.com
Background: Aerosol drug delivery to the lungs is known to be very inefficient during all
forms of noninvasive ventilation, especially when the aerosol is administered simultaneously …

[HTML][HTML] Cystic fibrosis-related diabetes (CFRD) and cognitive function in adults with cystic fibrosis

HK Chadwick, J Abbott, MA Hurley, L Dye… - Journal of Cystic …, 2022 - Elsevier
Background Being able to function cognitively is imperative for successful achievement in
school, working life, and disease self-management. Diabetes is known to cause changes in …

Hypertonic solution in severe COVID-19 patient: a potential adjuvant therapy

M Gennari-Felipe, L Borges, A Dermargos… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) features hyper-inflammation, cytokine storm,
neutrophil function changes, and sodium chloride (NaCl) homeostasis disruption, while the …

Nocturnal high-flow nasal cannula therapy and sinonasal symptoms during cystic fibrosis exacerbations

MD Davis, J Brockbank, R Hayden… - Respiratory …, 2023 - rc.rcjournal.com
BACKGROUND: Both nasal obstruction and sleep disturbance are common in patients with
cystic fibrosis (CF). In patients with obstructive sleep apnea (OSA), studies suggest that …

[PDF][PDF] 结肠癌中NMNAT2, p53 的表达及三者相关性研究

喻玉, 肖国辉, 王天刚, 赵龙, 杨伟兴 - 现代生物医学进展, 2019 - biomed.cnjournals.com
摘要目的: 检测结肠癌中烟酰胺核苷酸腺苷转移酶2 (Nicotinamide nucleotide adenosine
transferase 2, NMNAT2), p53 的表达并分析三者之间的关系. 方法: 免疫组化S-ABC 法(< 4 …