Members of the nerve growth factor (NGF) and glial cell line-derived neurotrophic factor
(GDNF) families—comprising neurotrophins and GDNF-family ligands (GFLs), respectively …

Cell-based therapy is emerging as a promising strategy for treating a wide range of human
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …

Intracerebral hemorrhage (ICH) is a cerebrovascular disease with high mortality and
morbidity, and the effective treatment is still lacking. We designed this study to investigate …

Object. Glial cell line-derived neurotrophic factor (GDNF) has demonstrated significant
antiparkinsonian actions in several animal models and in a recent pilot study in England in …

Dopamine‐releasing neurons within the Substantia nigra (SN DA) are particularly
vulnerable to degeneration compared to other dopaminergic neurons. The age‐dependent …

Shal-type (Kv4. x) K+ channels are expressed in a variety of tissue, with particularly high
levels in the brain and heart. These channels are the primary subunits that contribute to …

2004 Nature Pub lishing Group http://www. nature. com/natureneuroscience the axon
terminals in the striatum (Fig. 1d) or through the lateral ventricular route. Once rescued, the …

The GDNF family ligands (GFLs) signal through the canonical signaling receptor Ret and a
glycosyl-phosphatidylinositol-anchored co-receptor, GFRα. In recent years, signaling by …

In recent years, the population of neurons in the ventral tegmental area (VTA) and substantia
nigra (SN) has been examined at multiple levels. The results indicate that the projections …

Support of ageing neurons by endogenous neurotrophic factors such as glial cell line–
derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) may …