Over the past decade, RNA sequencing (RNA-seq) has become an indispensable tool for
transcriptome-wide analysis of differential gene expression and differential splicing of …

Motivation Although seldom acknowledged explicitly, count data generated by sequencing
platforms exist as compositions for which the abundance of each component (eg gene or …

When identifying differentially expressed genes between two conditions using human
population RNA-seq samples, we found a phenomenon by permutation analysis: two …

RNA-seq is currently considered the most powerful, robust and adaptable technique for
measuring gene expression and transcription activation at genome-wide level. As the …

Background The application of RNA-seq technology has become more extensive and the
number of analysis procedures available has increased over the past years. Selecting an …

Mounting evidence has shown that gut microbiome is associated with various cancers,
including gastrointestinal (GI) tract and non-GI tract cancers. But microbiome data have …

The F4/80 antigen, encoded by the Adgre1 locus, has been widely-used as a monocyte-
macrophage marker in mice, but its value as a macrophage marker in other species is …

The toxicogenomics field aims to understand and predict toxicity by using 'omics' data in
order to study systems-level responses to compound treatments. In recent years there has …

Abstract Background Though Illumina has largely dominated the RNA-Seq field, the
simultaneous availability of Ion Torrent has left scientists wondering which platform is most …

Transcriptional programs instruct the generation and maintenance of diverse subtypes of
neural cells, establishment of distinct brain regions, formation and function of neural circuits …