The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a
global health emergency, and its gene mutation and evolution further posed uncertainty of …

Genetically-characterizing full-length HIV-1 RNA is critical for identifying genetically-intact
genomes and for comparing these RNA genomes to proviral DNA. We have developed a …

A significant portion of genes in vertebrate genomes belongs to multigene families, with
each family containing several gene copies whose presence/absence, as well as isoform …

Direct methods for determining the fidelity of DNA polymerases are robust, with relatively
little sample manipulation before sequencing. In contrast, methods for measuring RNA …

Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic tests have
relied on RNA extraction followed by reverse transcription quantitative polymerase chain …

Microbial communities are composed of populations with vastly different abundances and
levels of metabolic and replicative activity, ranging from actively metabolizing and dividing to …

Multicopy ampliconic gene families on the Y chromosome play an important role in
spermatogenesis. Thus, studying their genetic variation in endangered great ape species is …

Snap‐frozen biopsies serve as a valuable clinical resource of archival material for disease
research, as they enable a comprehensive array of downstream analyses to be performed …

Short-read RNA-Seq analyses of grafted plants have led to the proposal that large numbers
of mRNAs move over long distances between plant tissues, acting as potential signals. The …

Background The ubiquitous presence of short tandem repeats (STRs) in virtually all
genomes implicates their functional relevance, while a widely-accepted definition of STR is …