Gene-environment interactions in Alzheimer's disease: a potential path to precision medicine
Alzheimer's disease (AD) is the leading cause of dementia in the United States and afflicts>
5.7 million Americans in 2018. Therapeutic options remain extremely limited to those that …
5.7 million Americans in 2018. Therapeutic options remain extremely limited to those that …
An integrative memory model of recollection and familiarity to understand memory deficits
Humans can recollect past events in details (recollection) and/or know that an object,
person, or place has been encountered before (familiarity). During the last two decades …
person, or place has been encountered before (familiarity). During the last two decades …
Cognitive Functioning of Unaffected First-degree Relatives of Individuals With Late-onset Alzheimer's Disease: A Systematic Literature Review and Meta-analysis
First-degree relatives of individuals with late-onset Alzheimer's disease (LOAD) are at
increased risk for developing dementia, yet the associations between family history of LOAD …
increased risk for developing dementia, yet the associations between family history of LOAD …
How many trials are required for parameter estimation in diffusion modeling? A comparison of different optimization criteria
Abstract Diffusion models (Ratcliff, 1978) make it possible to identify and separate different
cognitive processes underlying responses in binary decision tasks (eg, the speed of …
cognitive processes underlying responses in binary decision tasks (eg, the speed of …
Diffusion modeling and intelligence: Drift rates show both domain-general and domain-specific relations with intelligence.
Several previous studies reported relationships between speed of information processing as
measured with the drift parameter of the diffusion model (Ratcliff, 1978) and general …
measured with the drift parameter of the diffusion model (Ratcliff, 1978) and general …
Evidence accumulation models: Current limitations and future directions
NJ Evans, EJ Wagenmakers - 2019 - osf.io
Evidence accumulation models (EAMs) have been the dominant models of speeded
decision-making for several decades. These models propose that evidence accumulates for …
decision-making for several decades. These models propose that evidence accumulates for …
Age differences in diffusion model parameters: A meta-analysis
Older adults typically show slower response times in basic cognitive tasks than younger
adults. A diffusion model analysis allows the clarification of why older adults react more …
adults. A diffusion model analysis allows the clarification of why older adults react more …
Retest reliability of the parameters of the Ratcliff diffusion model
In the recent years, there is a growing interest to use the Ratcliff Diffusion Model (1978) for
diagnostic purposes as the parameters of the model capture interindividual differences in …
diagnostic purposes as the parameters of the model capture interindividual differences in …
Experimental validation of the diffusion model based on a slow response time paradigm
Abstract The diffusion model (Ratcliff, Psychol Rev 85 (2): 59–108, 1978) is a stochastic
model that is applied to response time (RT) data from binary decision tasks. The model is …
model that is applied to response time (RT) data from binary decision tasks. The model is …
Differential responses of primary neuron-secreted MCP-1 and IL-9 to type 2 diabetes and Alzheimer's disease-associated metabolites
Abstract Type 2 diabetes (T2D) is implicated as a risk factor for Alzheimer's disease (AD), the
most common form of dementia. In this work, we investigated neuroinflammatory responses …
most common form of dementia. In this work, we investigated neuroinflammatory responses …