The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

In humans, various genetic defects or age-related diseases, such as diabetic retinopathies,
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …

Although human epidemiological and genetic studies are essential to elucidate the
aetiology of normal and aberrant ocular development, animal models have provided us with …

Optic nerve degeneration caused by glaucoma is a leading cause of blindness worldwide.
Patients affected by the normal-pressure form of glaucoma are more likely to harbor risk …

Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

Glaucoma is a heterogeneous group of disorders that progressively lead to blindness due to
loss of retinal ganglion cells and damage to the optic nerve. It is a leading cause of …

Millions of people are affected by visual impairment and blindness globally, and the
prevalence of vision loss is likely to increase as we are living longer. However, many ocular …

Free swimming zebrafish larvae depend mainly on their sense of vision to evade predation
and to catch prey. Hence, there is strong selective pressure on the fast maturation of visual …

Rodent models have been extensively used to investigate the cause and mechanisms
behind Alzheimer's disease. Despite many years of intensive research using these models …