In the 1980s, David Barker and Colleagues proposed that the major causes of
cardiovascular and metabolic diseases have their roots in early development. There is now …

The natural aging process is carried out by a progressive loss of homeostasis leading to a
functional decline in cells and tissues. The accumulation of these changes stem from a …

Diabetic retinopathy remains the most common complication of diabetes mellitus and is a
leading cause of visual loss in industrialized nations. The clinicopathology of the diabetic …

Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

Amputation as a result of impaired wound healing is a serious complication of diabetes.
Inadequate angiogenesis contributes to poor wound healing in diabetic patients. Endothelial …

Diabetes in pregnancy has been shown to induce long-term effects in offspring. While
considerable attention is focused on the increased incidence of type 2 diabetes mellitus …

Adipose stromal cells (ASCs) express markers and functional properties of pericytes in vitro
and, in combination with endothelial cells (ECs), are able to establish multilayer functional …

The term “Endothelial progenitor cell”(EPC) has been used to describe multiple cell
populations that express endothelial surface makers and promote vascularisation. However …

Objective—We sought to identify and characterize 2 distinct populations of bona fide
circulating endothelial cells, including the endothelial colony-forming cell (ECFC), by …

Diabetes induces a decrease in the number and function of different pro-angiogenic cell
types generically designated as putative endothelial progenitor cells (EPC), which …