The transition from prenatal to postnatal life causes a significant increase in arterial oxygen
tension and the activation of metabolic pathways enabling the newborn's adaptation to the …

Acute lung injury (ALI) is an acute, diffuse inflammatory lung condition triggered by factors of
severe infections, trauma, shock, burns, ischemia-reperfusion, and mechanical ventilation. It …

Sepsis is characterized by a severe production of reactive oxygen species (ROS) and other
radical species with consequent oxidative stress. S-allyl cysteine (SAC) is a water-soluble …

Background Sepsis commonly progresses to acute lung injury and is associated with high
morbidity and mortality. Septic acute lung injury is characterized by severe oxidative stress …

Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the
leading causes of acute respiratory failure in many critical diseases and are among the main …

急性肺损伤(ALI) 及其诱发的急性呼吸窘迫综合征(ARDS) 是临床许多危重疾病发生急性呼吸
衰竭的主要原因, 是临床重大呼吸系统疾病之一, 病死率一直居高不下. 其病理基础常表现为肺内 …

Cell death is a normal phenomenon in the course of biological development, moreover,
which is also a prominent feature in lung exposed to hyperoxia. Severe hypoxia occurs in …

脓毒症是导致患者入住重症监护病房(ICU) 的主要病因之一. 虽然脓毒症及脓毒性休克的诊疗已
取得了一定的进展, 但其病死率仍然居高不下. 急性肺损伤是多种因素引起的肺毛细血管内皮 …

Background: Vascular endothelial growth factor (VEGF) in the thymus was mainly produced
by the thymic epithelial cells (TECs), the predominant component of the thymic …

目的通过蛋白质组学研究探讨高氧暴露后幼鼠Ⅱ 型肺泡上皮细胞(AECⅡ) 的损伤机制.
方法将早产SD 大鼠原代AECⅡ 细胞分为常氧组和高氧组, 分别置于常氧(21% O2) 和高氧(95 …