Growth hormone (GH) research and its clinical application for the treatment of growth
disorders span more than a century. During the first half of the 20th century, clinical …

The genetic basis for combined pituitary hormone deficiency (CPHD) is complex, involving
30 genes in a variety of syndromic and nonsyndromic presentations. Molecular diagnosis of …

Pituitary stalk interruption syndrome (PSIS) is a congenital pituitary anatomical defect. This
syndrome is an antenatal developmental defect belonging to the holoprosencephaly …

Introduction: Congenital hypopituitarism (CH) is characterized by a deficiency of one or more
pituitary hormones. The pituitary gland is a central regulator of growth, metabolism, and …

Pituitary stalk interruption syndrome is a rare disorder characterized by an absent or ectopic
posterior pituitary, interrupted pituitary stalk and anterior pituitary hypoplasia, as well as in …

Hypopituitarism is defined as one or more partial or complete pituitary hormone deficiencies,
which are related to the anterior and/or posterior gland and can have an onset in childhood …

Background Patients with pituitary stalk interruption syndrome (PSIS) are initially referred for
hypoglycemia during the neonatal period or growth retardation during childhood. PSIS is …

Context: Pituitary stalk interruption syndrome (PSIS) is a rare, congenital anomaly of the
pituitary gland characterized by pituitary gland insufficiency, thin or discontinuous pituitary …

Pituitary stalk interruption syndrome (PSIS) is a rare congenital defect manifesting with
varying degrees of pituitary hormone deficiency. The signs and symptoms of PSIS during the …

Context The international GENHYPOPIT network collects phenotypical data and screens
genetic causes of non‐acquired hypopituitarism. Aims To describe main phenotype patterns …