The crucial role of genome-wide genetic variation in conservation

M Kardos, EE Armstrong… - Proceedings of the …, 2021 - National Acad Sciences
The unprecedented rate of extinction calls for efficient use of genetics to help conserve
biodiversity. Several recent genomic and simulation-based studies have argued that the …

Inbreeding depression explains killer whale population dynamics

M Kardos, Y Zhang, KM Parsons, H Kang… - Nature Ecology & …, 2023 - nature.com
Understanding the factors that cause endangered populations to either grow or decline is
crucial for preserving biodiversity. Conservation efforts often address extrinsic threats, such …

The ecological causes and consequences of hard and soft selection

DA Bell, RP Kovach, ZL Robinson, AR Whiteley… - Ecology …, 2021 - Wiley Online Library
Interactions between natural selection and population dynamics are central to both
evolutionary‐ecology and biological responses to anthropogenic change. Natural selection …

Functional genomic diversity is correlated with neutral genomic diversity in populations of an endangered rattlesnake

S Mathur, AJ Mason, GS Bradburd… - Proceedings of the …, 2023 - National Acad Sciences
Theory predicts that genetic erosion in small, isolated populations of endangered species
can be assessed using estimates of neutral genetic variation, yet this widely used approach …

Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex

C Grossen, F Guillaume, LF Keller, D Croll - Nature communications, 2020 - nature.com
Human activity has caused dramatic population declines in many wild species. The resulting
bottlenecks have a profound impact on the genetic makeup of a species with unknown …

IUCN Red List and the value of integrating genetics

BA Garner, S Hoban, G Luikart - Conservation Genetics, 2020 - Springer
Many species on endangered species lists such as the IUCN Red List (RL) are categorized
using demographic factors such as numbers of mature individuals. Genetic factors are not …

Distribution, status, and recent population dynamics of Alpine ibex Capra ibex in Europe

A Brambilla, A Von Hardenberg, L Nelli… - Mammal …, 2020 - Wiley Online Library
Despite its recent successful and well‐documented reintroduction history, a comprehensive
and current update of the distribution and status of the Alpine ibex Capra ibex is lacking. As …

Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal

MA Stoffel, SE Johnston, JG Pilkington… - Nature …, 2021 - nature.com
Inbreeding depression is ubiquitous, but we still know little about its genetic architecture and
precise effects in wild populations. Here, we combine long-term life-history data with 417 K …

Genetic rescue remains underused for aiding recovery of federally listed vertebrates in the United States

SW Fitzpatrick, C Mittan-Moreau, M Miller… - Journal of …, 2023 - academic.oup.com
Restoring gene flow among fragmented populations is discussed as a potentially powerful
management strategy that could reduce inbreeding depression and cause genetic rescue …

Conservation management strategy impacts inbreeding and mutation load in scimitar-horned oryx

E Humble, MA Stoffel, K Dicks… - Proceedings of the …, 2023 - National Acad Sciences
In an age of habitat loss and overexploitation, small populations, both captive and wild, are
increasingly facing the effects of isolation and inbreeding. Genetic management has …