The roundworm Caenorhabditis elegans has risen to the status of a top model organism for
biological research in the last fifty years. Among laboratory animals, this tiny nematode is …

Pleiotropy is the well-established phenomenon of a single gene affecting multiple traits. It
has long played a central role in theoretical, experimental, and clinical research in genetics …

I propose a reconceptualization of key phenomena important in the study of emotion—those
phenomena that reflect functions and circuits related to survival, and that are shared by …

Studies in model organisms have yielded considerable insights into the etiology of disease
and our understanding of evolutionary processes. Caenorhabditis elegans is among the …

The search for the alleles that matter, the quantitative trait nucleotides (QTNs) that underlie
heritable variation within populations and divergence among them, is a popular pursuit. But …

The~ 100 MB genome of C. elegans codes for~ 20,000 protein-coding genes many of which
are required for the function of the nervous system, composed of 302 neurons in the adult …

In the laboratory, the nematode Caenorhabditis elegans lives on the surface of nutrient agar
in Petri dishes, feeding on a lawn of the uracil auxotroph strain OP50, an Escherichia coli …

The nematode Caenorhabditis elegans is central to research in molecular, cell and
developmental biology, but nearly all of this research has been conducted on a single strain …

Abstract Background The nematode Caenorhabditis elegans is a major model organism in
laboratory biology. Very little is known, however, about its ecology, including where it …

Using low-cost automated tracking microscopes, we have generated a behavioral database
for 305 Caenorhabditis elegans strains, including 76 mutants with no previously described …