Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers

NH Amin, MT Elsaadi, SS Zaki, HM Abdel-Rahman - Bioorganic Chemistry, 2020 - Elsevier
Herein, we report the synthesis of novel 2-substituted styrylquinazolines conjugated with
aniline or sulfonamide moieties, anticipated to act as potent anticancer therapeutic agents …

[PDF][PDF] New generation of quinazolinone derivatives as potent antimicrobial agents

PR Patel, H Joshi, U Shah, M Bapna… - Asian Pac J Health …, 2021 - researchgate.net
Heterocyclic compounds play tremendous roles and wide applications in the field of
medicinal chemistry. Among them, quinazoline derivatives have been found to be exhibit …

[PDF][PDF] Recent advances in synthesis of quinazolines: A review

S Metri, S Melavanki, B Dashyal… - International Journal of …, 2022 - ijpsi.org
Most medications and pharmacologically significant compounds have heterocyclic ring
structures, and the presence of hetero atoms or groups reveals preferred pharmacological …

Synthesis and characterization of a series of phenyl piperazine based ligands

R Kant, T Kaur, Z Hilal, N Aggarwal… - Journal of physics …, 2020 - iopscience.iop.org
Piperazine based compounds are gaining more attention in today's research as the
piperazine nucleus is found in many biologically active compounds. Substitution in nitrogen …

[PDF][PDF] Synthesis, screening of novel 1-substituted-3-(4-oxo-2-phenylquinazolin-3 (4H)-yl) urea and thiourea analogues as potent antibacterials

SR Dhokale, SR Thakar, DA Bansode… - Int J Pharm Pharm …, 2019 - academia.edu
Objective: The proposed study is an attempt to determine antibacterial activity of synthesized
novel 1-substituted-3-(4-oxo-2-phenylquinazolin-3 (4H)-yl) urea and thiourea analogues as …