[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics
DNA methylation plays a vital role in epigenetic regulation in both plants and animals, and
typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …
typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …
5-Hydroxymethylcytosine: The many faces of the sixth base of mammalian DNA
E Kriukienė, M Tomkuvienė… - Chemical Society …, 2024 - pubs.rsc.org
Epigenetic phenomena play a central role in cell regulatory processes and are important
factors for understanding complex human disease. One of the best understood epigenetic …
factors for understanding complex human disease. One of the best understood epigenetic …
[HTML][HTML] cgNA+ web: A visual interface to the cgNA+ sequence-dependent statistical mechanics model of double-stranded nucleic acids
R Sharma, AS Patelli, L De Bruin… - Journal Of Molecular …, 2023 - Elsevier
The sequence-dependent statistical mechanics of double-stranded nucleic acid, or dsNA, is
believed to be essential in its biological functions. In turn, the equilibrium statistical …
believed to be essential in its biological functions. In turn, the equilibrium statistical …
Unexpected thermodynamic signature for the interaction of hydroxymethylated DNA with MeCP2
D Ortega-Alarcon, R Claveria-Gimeno, S Vega… - International Journal of …, 2023 - Elsevier
Hydroxymethylated cytosine (5hmC) is a stable DNA epigenetic mark recognized by methyl-
CpG binding protein 2 (MeCP2), which acts as a transcriptional regulator and a global …
CpG binding protein 2 (MeCP2), which acts as a transcriptional regulator and a global …
Studies of the Mechanism of Nucleosome Dynamics: A Review on Multifactorial Regulation from Computational and Experimental Cases
D Shi, Y Huang, C Bai - Polymers, 2023 - mdpi.com
The nucleosome, which organizes the long coil of genomic DNA in a highly condensed,
polymeric way, is thought to be the basic unit of chromosomal structure. As the most …
polymeric way, is thought to be the basic unit of chromosomal structure. As the most …
Prediction of DNA Methylation based on Multi-dimensional feature encoding and double convolutional fully connected convolutional neural network
W Hu, L Guan, M Li - PLoS Computational Biology, 2023 - journals.plos.org
DNA methylation takes on critical significance to the regulation of gene expression by
affecting the stability of DNA and changing the structure of chromosomes. DNA methylation …
affecting the stability of DNA and changing the structure of chromosomes. DNA methylation …