Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications

A Caturano, M D'Angelo, A Mormone, V Russo… - Current Issues in …, 2023 - mdpi.com
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

SGLT2 inhibitors in the treatment of diabetic kidney disease: more than just glucose regulation

J Klen, V Dolžan - Pharmaceutics, 2023 - mdpi.com
Diabetic kidney disease (DKD) is a severe and common complication and affects a quarter
of patients with type 2 diabetes mellitus (T2DM). Oxidative stress and inflammation related to …

Oral semaglutide improves body composition and preserves lean mass in patients with type 2 diabetes: a 26-week prospective real-life study

S Volpe, G Lisco, M Fanelli, D Racaniello… - Frontiers in …, 2023 - frontiersin.org
Background Oral semaglutide is the first glucagon-like peptide-1 receptor agonist (GLP-
1RA) designed for oral administration; it offers a promising opportunity to facilitate an early …

Frail hypertensive older adults with prediabetes and chronic kidney disease: insights on organ damage and cognitive performance-preliminary results from the …

G Santulli, V Visco, M Ciccarelli, MNV Ferrante… - Cardiovascular …, 2024 - Springer
Background Hypertension and chronic kidney disease (CKD) pose significant public health
challenges, sharing intertwined pathophysiological mechanisms. Prediabetes is recognized …

Risk Factors of Chronic Kidney Disease Progression: Between Old and New Concepts

F Mallamaci, G Tripepi - Journal of Clinical Medicine, 2024 - mdpi.com
Chronic kidney disease (CKD) is a condition characterized by the gradual loss of kidney
function over time and it is a worldwide health issue. The estimated frequency of CKD is …

Association between adipocytokines and diabetic retinopathy: a systematic review and meta-analysis

Y Jiang, H Fan, J Xie, Y Xu, X Sun - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Diabetic retinopathy (DR) is a common complication of diabetes. The
adipocytokines are closely associated with the occurrence and development of diabetes and …

Glycemic control and cardiovascular outcomes in patients with diabetes and coronary artery disease according to triglyceride-glucose index: a large-scale cohort …

Z Lin, J He, S Yuan, C Song, X Bian, M Yang… - Cardiovascular …, 2024 - Springer
Background The role of triglyceride-glucose (TyG) index, an insulin resistance indicator, in
glycemic management for diabetic patients with coronary artery disease (CAD) was still …

The association between distal symmetric polyneuropathy in diabetes with all-cause mortality–a meta-analysis

OE Vági, MM Svébis, BA Domján, AE Körei… - Frontiers in …, 2023 - frontiersin.org
Background Distal symmetric polyneuropathy (DSPN) is a common microvascular
complication of both type 1 and 2 diabetes with substantial morbidity burden and reduced …

The effects of Sodium-glucose cotransporter 2 inhibitors on adipose tissue in patients with type 2 diabetes: A meta-analysis of randomized controlled trials

X Liu, Y Chen, T Liu, L Cai, X Yang… - Frontiers in Endocrinology, 2023 - frontiersin.org
Purpose To systematically evaluate the effect of Sodium-glucose cotransporter 2 (SGLT2)
inhibitors on adipose tissue in patients with type 2 diabetes. Methods We searched PubMed …

Urinary metabolites associate with the presence of diabetic kidney disease in type 2 diabetes and mediate the effect of inflammation on kidney complication

C Shi, Y Wan, A He, X Wu, X Shen, X Zhu, J Yang… - Acta Diabetologica, 2023 - Springer
Aims Diabetic kidney disease (DKD) is the one of the leading causes of end-stage kidney
disease. Unraveling novel biomarker signatures capable to identify patients with DKD is …