Redundant angiogenic signaling and tumor drug resistance

RN Gacche, YG Assaraf - Drug Resistance Updates, 2018 - Elsevier
Angiogenesis research in the past two decades has contributed significantly towards
understanding the molecular pathophysiology of cancer progression and inspired target …

Role of the tumor stroma in resistance to anti-angiogenic therapy

EJM Huijbers, JR van Beijnum, VL Thijssen… - Drug Resistance …, 2016 - Elsevier
Several angiogenesis inhibitors are currently used in the clinic for treatment of cancer. While
anti-angiogenesis treatment can improve treatment outcome, the overall benefit on patient …

Pericytes in glioblastomas: multifaceted role within tumor microenvironments and potential for therapeutic interventions

A Sattiraju, A Mintz - Pericyte Biology in Disease, 2019 - Springer
Glioblastoma (GBM) is an aggressive and lethal disease that often results in a poor
prognosis. Unlike most solid tumors, GBM is characterized by diffuse infiltrating margins …

Inhibition of Lysyl Oxidases Impairs Migration and Angiogenic Properties of Tumor‐Associated Pericytes

AL Ribeiro, C Kaid, PBG Silva, BA Cortez… - Stem Cells …, 2017 - Wiley Online Library
Pericytes are important cellular components of the tumor microenviroment with established
roles in angiogenesis and metastasis. These two cancer hallmarks are modulated by …

Pericytic (Perivascular) Tumors

HS Kang, SH Hong, JY Choi, HJ Yoo, HS Kang… - Oncologic Imaging: Soft …, 2017 - Springer
Pericytes are contractile cells that wrap around the endothelial cells of capillaries and
venules throughout the body. These supportive perivascular cells are essential to …