RAS/MAPK signaling functions in oxidative stress, DNA damage response and cancer progression

S Rezatabar, A Karimian, V Rameshknia… - Journal of cellular …, 2019 - Wiley Online Library
Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution
network that regulates several physiological processes, like cell growth, differentiation, and …

Role of p38 MAP kinase signal transduction in solid tumors

HK Koul, M Pal, S Koul - Genes & cancer, 2013 - journals.sagepub.com
Mitogen-activated protein kinases (MAPKs) mediate a wide variety of cellular behaviors in
response to extracellular stimuli. One of the main subgroups, the p38 MAP kinases, has …

[HTML][HTML] The anti-inflammatory effects of vitamin D in tumorigenesis

W Liu, L Zhang, HJ Xu, Y Li, CM Hu, JY Yang… - International journal of …, 2018 - mdpi.com
In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …

Androgen receptors in hormone-dependent and castration-resistant prostate cancer

AA Shafi, AE Yen, NL Weigel - Pharmacology & therapeutics, 2013 - Elsevier
Abstract In the United States, prostate cancer (PCa) is the most commonly diagnosed non-
cutaneous cancer in males and the second leading cause of cancer-related death for men …

Curcumin and cancer: an “old-age” disease with an “age-old” solution

P Anand, C Sundaram, S Jhurani, AB Kunnumakkara… - Cancer letters, 2008 - Elsevier
Cancer is primarily a disease of old age, and that life style plays a major role in the
development of most cancers is now well recognized. While plant-based formulations have …

The metastasis-promoting roles of tumor-associated immune cells

HA Smith, Y Kang - Journal of molecular medicine, 2013 - Springer
Tumor metastasis is driven not only by the accumulation of intrinsic alterations in malignant
cells, but also by the interactions of cancer cells with various stromal cell components of the …

Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D

AV Krishnan, D Feldman - Annual review of pharmacology and …, 2011 - annualreviews.org
Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an
anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro …

[HTML][HTML] Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

SP Gao, KG Mark, K Leslie, W Pao… - The Journal of …, 2007 - Am Soc Clin Investig
Persistently activated or tyrosine-phosphorylated STAT3 (pSTAT3) is found in 50% of lung
adenocarcinomas. pSTAT3 is found in primary adenocarcinomas and cell lines harboring …

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

KS Hoek, NC Schlegel, P Brafford, A Sucker… - Pigment cell …, 2006 - Wiley Online Library
The molecular biology of metastatic potential in melanoma has been studied many times
previously and changes in the expression of many genes have been linked to metastatic …

Active nanodiamond hydrogels for chemotherapeutic delivery

H Huang, E Pierstorff, E Osawa, D Ho - Nano letters, 2007 - ACS Publications
Nanodiamond materials can serve as highly versatile platforms for the controlled
functionalization and delivery of a wide spectrum of therapeutic elements. In this work …