[HTML][HTML] Understanding and targeting prostate cancer cell heterogeneity and plasticity

DG Tang - Seminars in cancer biology, 2022 - Elsevier
Prostate cancer (PCa) is a prevalent malignancy that occurs primarily in old males. Prostate
tumors in different patients manifest significant inter-patient heterogeneity with respect to …

Key genes and molecular mechanisms related to Paclitaxel Resistance

AI Alalawy - Cancer Cell International, 2024 - Springer
Paclitaxel is commonly used to treat breast, ovarian, lung, esophageal, gastric, pancreatic
cancer, and neck cancer cells. Cancer recurrence is observed in patients treated with …

Membrane metalloendopeptidase (MME) is positively correlated with systemic lupus erythematosus and may inhibit the occurrence of breast cancer

J Ding, C Li, K Shu, W Chen, C Cai, X Zhang, W Zhang - Plos one, 2023 - journals.plos.org
Background Patients with systemic lupus erythematosus (SLE) have a lower risk of breast
cancer (BRCA) than the general population. In this study, we explored the underlying …

Identification of potential biomarkers for cancer cachexia and anti-Fn14 therapy

Z Cao, IJ Burvenich, K Zhao, C Senko, J Glab… - Cancers, 2022 - mdpi.com
Simple Summary Cancer cachexia is an underestimated condition with huge impact on
survival and quality of life for many cancer patients. Currently, there is no reliable diagnosis …

Differential expression analysis revealing CLCA1 to be a prognostic and diagnostic biomarker for colorectal cancer

FZ Wei, SW Mei, ZJ Wang, JN Chen, HY Shen… - Frontiers in …, 2020 - frontiersin.org
Colorectal cancer (CRC) is a common malignant tumor of the digestive tract and lacks
specific diagnostic markers. In this study, we utilized 10 public datasets from the NCBI Gene …

Revealing the pathogenesis of gastric intestinal metaplasia based on the mucosoid air-liquid interface

S Liu, H Wen, F Li, X Xue, X Sun, F Li, R Hu… - Journal of Translational …, 2024 - Springer
Background Gastric intestinal metaplasia (GIM) is an essential precancerous lesion.
Although the reversal of GIM is challenging, it potentially brings a state-to-art strategy for …

Novel stemness-related gene signature predicting prognosis and indicating a different immune microenvironment in hnscc

Y Luo, WB Xu, B Ma, Y Wang - Frontiers in genetics, 2022 - frontiersin.org
Background: The head and neck squamous cell carcinomas (HNSCC) is one of the most
frequent cancers in the world, with an unfavorable prognosis. Cancer stem cells (CSCs) …

Validation of novel molecular imaging targets identified by functional genomic mRNA profiling to detect dysplasia in Barrett's esophagus

X Zhao, RY Gabriëls, WTR Hooghiemstra, M Koller… - Cancers, 2022 - mdpi.com
Simple Summary Barrett's esophagus (BE) is the precursor of esophageal adenocarcinoma
(EAC). Dysplastic BE (DBE), including low-grade dysplasia (LGD) and high-grade dysplasia …

Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells

MJ Akbar, PCL Ferreira, M Giorgetti… - Beilstein journal of …, 2019 - beilstein-journals.org
Background: Gastrin-releasing peptide is a member of the bombesin family of peptides. Its
cognate receptor, gastrin releasing peptide receptor (GRPR), is widely expressed in cancers …

Genes associated with diagnosis and prognosis of Burkitt lymphoma

A Doughan, SP Salifu - IET Systems Biology, 2022 - Wiley Online Library
Burkitt lymphoma (BL) is one of the most aggressive forms of non‐Hodgkin's lymphomas that
affect children and young adults. The expression of genes and other molecular markers …