Harnessing genomic information for livestock improvement
M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …
2050. Meeting this demand in a way that has a minimal impact on the environment will …
Genomic selection and its research progress in aquaculture breeding
H Song, T Dong, X Yan, W Wang, Z Tian… - Reviews in …, 2023 - Wiley Online Library
Since its introduction in 2001, genomic selection (GS) has progressed rapidly. As a research
and application hot topic, GS has led to a revolution in the field of animal and plant breeding …
and application hot topic, GS has led to a revolution in the field of animal and plant breeding …
Signatures of negative selection in the genetic architecture of human complex traits
We develop a Bayesian mixed linear model that simultaneously estimates single-nucleotide
polymorphism (SNP)-based heritability, polygenicity (proportion of SNPs with nonzero …
polymorphism (SNP)-based heritability, polygenicity (proportion of SNPs with nonzero …
Genomic selection models double the accuracy of predicted breeding values for bacterial cold water disease resistance compared to a traditional pedigree-based …
RL Vallejo, TD Leeds, G Gao, JE Parsons… - Genetics Selection …, 2017 - Springer
Background Previously, we have shown that bacterial cold water disease (BCWD)
resistance in rainbow trout can be improved using traditional family-based selection, but …
resistance in rainbow trout can be improved using traditional family-based selection, but …
[PDF][PDF] Current status of genomic evaluation
Early application of genomic selection relied on SNP estimation with phenotypes or de-
regressed proofs (DRP). Chips of 50k SNP seemed sufficient for an accurate estimation of …
regressed proofs (DRP). Chips of 50k SNP seemed sufficient for an accurate estimation of …
Non-additive effects in genomic selection
In the last decade, genomic selection has become a standard in the genetic evaluation of
livestock populations. However, most procedures for the implementation of genomic …
livestock populations. However, most procedures for the implementation of genomic …
Genetic evaluation using single-step genomic best linear unbiased predictor in American Angus
Predictive ability of genomic EBV when using single-step genomic BLUP (ssGBLUP) in
Angus cattle was investigated. Over 6 million records were available on birth weight (BiW) …
Angus cattle was investigated. Over 6 million records were available on birth weight (BiW) …
Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle
Background Single-step genomic best linear unbiased prediction (SSGBLUP) is a
comprehensive method for genomic prediction. Point estimates of marker effects from …
comprehensive method for genomic prediction. Point estimates of marker effects from …
Inexpensive computation of the inverse of the genomic relationship matrix in populations with small effective population size
I Misztal - Genetics, 2016 - academic.oup.com
Many computations with SNP data including genomic evaluation, parameter estimation, and
genome-wide association studies use an inverse of the genomic relationship matrix. The …
genome-wide association studies use an inverse of the genomic relationship matrix. The …
Incorporation of causative quantitative trait nucleotides in single-step GBLUP
Background Much effort is put into identifying causative quantitative trait nucleotides (QTN)
in animal breeding, empowered by the availability of dense single nucleotide polymorphism …
in animal breeding, empowered by the availability of dense single nucleotide polymorphism …