Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous
system (CNS) with unknown etiology. Several factors were hypothesized to be involved in …

Although progesterone is a steroid hormone mainly associated with female reproductive
functions, such as uterine receptivity and maintenance of pregnancy, accumulating data …

Although behavior may often be a fairly direct target of natural or sexual selection, it cannot
evolve without changes in subordinate traits that cause or permit its expression. In principle …

J. Neurochem.(2012) 122, 260–271. Abstract The male gender is determined by the sex‐
determining region on the Y chromosome (SRY) transcription factor. The unexpected action …

Steroid hormones play an influential role in neural development. In addition to androgens
and estrogens of fetal and neonatal origin, the developing brain may also be exposed to …

Sex hormones exert differential effects on a variety of sensitive tissues like the reproductive
tract, gonads, liver, bone and adipose tissue, among others. In the brain, sex hormones act …

Progesterone participates in the regulation of several functions in mammals, including brain
differentiation and dopaminergic transmission, but the role of progesterone in dopaminergic …

Sex differences are present in psychiatric disorders associated with disrupted dopamine
function, and thus, sex differences in dopamine neurobiology may underlie these clinical …

Embryonic stem cells (ESC) can differentiate to derivatives of the three embryonic germ
layers. Dopamine neurons have been produced from mouse and human ESC. This in vitro …

Publisher Summary This chapter reviews evidence that PR-dopamine modulates female
sexual behavior by a mechanism that involves convergence of two distinct pathways …