An update on the molecular biology of glioblastoma, with clinical implications and progress in its treatment
E Verdugo, I Puerto, MÁ Medina - Cancer Communications, 2022 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …
Tracking tumor heterogeneity and progression with near‐infrared II fluorophores
Q Xin, H Ma, H Wang, XD Zhang - Exploration, 2023 - Wiley Online Library
Heterogeneous cells are the main feature of tumors with unique genetic and phenotypic
characteristics, which can stimulate differentially the progression, metastasis, and drug …
characteristics, which can stimulate differentially the progression, metastasis, and drug …
[HTML][HTML] High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers
Precision medicine is critically dependent on better methods for diagnosing and staging
disease and predicting drug response. Histopathology using hematoxylin and eosin (H&E) …
disease and predicting drug response. Histopathology using hematoxylin and eosin (H&E) …
[HTML][HTML] Advances in glioblastoma therapy: an update on current approaches
Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …
[HTML][HTML] Glioma stem cells: novel data obtained by single-cell sequencing
A Gisina, I Kholodenko, Y Kim, M Abakumov… - International journal of …, 2022 - mdpi.com
Glioma is the most common type of primary CNS tumor, composed of cells that resemble
normal glial cells. Recent genetic studies have provided insight into the inter-tumoral …
normal glial cells. Recent genetic studies have provided insight into the inter-tumoral …
[HTML][HTML] Artificial intelligence in neuro-oncology: advances and challenges in brain tumor diagnosis, prognosis, and precision treatment
This review delves into the most recent advancements in applying artificial intelligence (AI)
within neuro-oncology, specifically emphasizing work on gliomas, a class of brain tumors …
within neuro-oncology, specifically emphasizing work on gliomas, a class of brain tumors …
[HTML][HTML] Glioblastoma therapy: past, present and future
E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
[HTML][HTML] A novel therapeutic strategy of multimodal nanoconjugates for state-of-the-art brain tumor phototherapy
Background The outcome of phototherapy, including photothermal therapy (PTT) and
photodynamic therapy (PDT) for glioblastoma multiforme (GBM), is disappointing due to …
photodynamic therapy (PDT) for glioblastoma multiforme (GBM), is disappointing due to …
[HTML][HTML] Nanoparticle strategies to improve the delivery of anticancer drugs across the blood–brain barrier to treat brain tumors
WJF Vanbilloen, JS Rechberger, JB Anderson… - Pharmaceutics, 2023 - mdpi.com
Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …
that occur within the brain and spinal cord. Although significant advances in our …
Cellular senescence in glioma
Introduction Glioma is the most common primary brain tumor and is often associated with
treatment resistance and poor prognosis. Standard treatment typically involves radiotherapy …
treatment resistance and poor prognosis. Standard treatment typically involves radiotherapy …