The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a
protein, but this does not mean that such RNAs do not contain information nor have function …

Non-protein-coding sequences increasingly dominate the genomes of multicellular
organisms as their complexity increases, in contrast to protein-coding genes, which remain …

Sex in mammals is determined in the fetal gonad by the presence or absence of the Y
chromosome gene Sry, which controls whether bipotential precursor cells differentiate into …

It is usually thought that the development of complex organisms is controlled by protein
regulatory factors and morphogenetic signals exchanged between cells and differentiating …

Foxl2 is a member of the large family of Forkhead Box (Fox) domain transcription factors. It
emerged during the last 15 years as a key player in ovarian differentiation and oogenesis in …

There are numerous examples of sex differences in brain and behavior and in susceptibility
to a broad range of brain diseases. For example, gene expression is sexually dimorphic …

In mammals, sex determination is a process through which the gonad is committed to
differentiate into a testis or an ovary. This process relies on a delicate balance between …

The RNA-binding proteins FCA and FPA were identified based on their repression of the
flowering time regulator FLC but have since been shown to have widespread roles in the …

MicroRNAs (miRNAs) have been indicated to play key roles in ovarian follicular
development. However, little is known about how the miRNA gene expression itself is …

A Foxl2 ortholog has been identified in a lophotrochozoa, the pacific oyster, which is a
successive irregular hermaphrodite mollusc. Its cDNA has been called Cg-Foxl2 …