[HTML][HTML] Mechanisms of cisplatin-induced acute kidney injury: pathological mechanisms, pharmacological interventions, and genetic mitigations
KR McSweeney, LK Gadanec, T Qaradakhi, BA Ali… - Cancers, 2021 - mdpi.com
Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …
[HTML][HTML] Oral mucosal epithelial cells
S Groeger, J Meyle - Frontiers in immunology, 2019 - frontiersin.org
Cellular Phenotype and Apoptosis: The function of epithelial tissues is the protection of the
organism from chemical, microbial, and physical challenges which is indispensable for …
organism from chemical, microbial, and physical challenges which is indispensable for …
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets
V Kumar - International immunopharmacology, 2020 - Elsevier
Cytokine storm generates during various systemic acute infections, including sepsis and
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …
[HTML][HTML] The function and clinical application of extracellular vesicles in innate immune regulation
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
[HTML][HTML] Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines
Toll-like receptors (TLRs) are transmembrane proteins belonging to the family of pattern-
recognition receptors. They function as sensors of invading pathogens through recognition …
recognition receptors. They function as sensors of invading pathogens through recognition …
Recent clinical trends in Toll‐like receptor targeting therapeutics
Toll‐like receptors (TLRs) are germline‐encoded receptors that are central to innate and
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …
adaptive immune responses. Owing to their vital role in inflammation, TLRs are rational …
Urinary tract infection: Pathogenicity, antibiotic resistance and development of effective vaccines against Uropathogenic Escherichia coli
Urinary tract infections (UTIs) are recognized as one of the most common infectious
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …
The history of Toll-like receptors—redefining innate immunity
The discovery of Toll-like receptors (TLRs) was an important event for immunology research
and was recognized as such with the awarding of the 2011 Nobel Prize in Physiology or …
and was recognized as such with the awarding of the 2011 Nobel Prize in Physiology or …
Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
[HTML][HTML] The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
T Kawai, S Akira - Nature immunology, 2010 - nature.com
The discovery of Toll-like receptors (TLRs) as components that recognize conserved
structures in pathogens has greatly advanced understanding of how the body senses …
structures in pathogens has greatly advanced understanding of how the body senses …