Transcription regulation networks control the expression of genes. The transcription
networks of well-studied microorganisms appear to be made up of a small set of recurring …

Evolving studies with several different targeted therapeutic agents are demonstrating that
patients with genomic alterations of the target, including amplification, translocation and …

Gene and protein set enrichment analysis is a critical step in the analysis of data collected
from omics experiments. Enrichr is a popular gene set enrichment analysis web-server …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

A cell's behavior is a consequence of the complex interactions between its numerous
constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling …

Abstract Systems pharmacology is an emerging area of pharmacology which utilizes
network analysis of drug action as one of its approaches. By considering drug actions and …

Understanding the dynamics and variability of protein circuitry requires accurate
measurements in living cells as well as theoretical models. To address this, we employed …

Cellular signal transduction is a complex process involving protein-protein interactions
(PPIs) that transmit information. For example, signals from the plasma membrane may be …

DNA nanotechnology relies on the structural and functional information encoded in nucleic
acids. Specifically, the sequence‐guided reconfiguration of nucleic acids by auxiliary …

N-myristoylation is a common form of co-translational protein fatty acylation resulting from
the attachment of myristate to a required N-terminal glycine residue,. We show that …