Ophthalmic biomarkers have long played a critical role in diagnosing and managing ocular
diseases. Oculomics has emerged as a field that utilizes ocular imaging biomarkers to …

Background A connection has been established between ocular structural changes and
various neurodegenerative diseases. Several studies utilizing optical coherence …

Background Cognitive decline has been reported in premanifest and manifest Huntington's
disease but reliable biomarkers are lacking. Inner retinal layer thickness seems to be a good …

Objective To characterize retinal and choroidal microvascular and structural changes in
patients who are gene positive for mutant huntingtin protein (mHtt) with symptoms of …

Background The unique neurovascular structure of the retina has provided an opportunity to
observe brain pathology in many neurological disorders. However, such studies on …

The intricate functionality of the vertebrate retina relies on the interplay between
neurotransmitter activity and calcium (Ca2+) dynamics, offering important insights into …

Purpose: Retinal images contain rich biomarker information for neurodegenerative disease.
Recently, deep learning models have been used for automated neurodegenerative disease …

Purpose Huntington's Disease (HD) is a fully penetrant neurodegenerative disease leading
to cognitive and motor disturbances. The retina may serve as a structural and functional …

The eye serves as a unique window into systemic health, offering clinicians a valuable
opportunity for early detection and targeted treatment. Against this backdrop, advancements …

The retina shares a common embryological origin with the brain and both organs have
numerous anatomical and functional commonalities. The retina is the only portion of the …