Pulmonary immune dysregulation and viral persistence during HIV infection
Y Alexandrova, CT Costiniuk, MA Jenabian - Frontiers in immunology, 2022 - frontiersin.org
Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …
SGLT2 inhibition with empagliflozin attenuates myocardial oxidative stress and fibrosis in diabetic mice heart
C Li, J Zhang, M Xue, X Li, F Han, X Liu, L Xu… - Cardiovascular …, 2019 - Springer
Background Hyperglycaemia associated with myocardial oxidative stress and fibrosis is the
main cause of diabetic cardiomyopathy. Empagliflozin, a sodium-glucose cotransporter 2 …
main cause of diabetic cardiomyopathy. Empagliflozin, a sodium-glucose cotransporter 2 …
HIV-1 latency and viral reservoirs: existing reversal approaches and potential technologies, targets, and pathways involved in HIV latency studies
Eradication of latent human immunodeficiency virus (HIV) infection is a global health
challenge. Reactivation of HIV latency and killing of virus-infected cells, the so-called “kick …
challenge. Reactivation of HIV latency and killing of virus-infected cells, the so-called “kick …
MiR-130a-3p Alleviates Liver Fibrosis by Suppressing HSCs Activation and Skewing Macrophage to Ly6Clo Phenotype
L Liu, P Wang, YS Wang, YN Zhang, C Li… - Frontiers in …, 2021 - frontiersin.org
Emerging evidences have highlighted the crucial role of microRNAs (miRNAs) in the liver
cirrhosis, but the relationship between miR-130a-3p and liver cirrhosis is not entirely clear …
cirrhosis, but the relationship between miR-130a-3p and liver cirrhosis is not entirely clear …
Isoliquiritigenin inhibits TGF-β 1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells
Isoliquiritigenin (ISL), a natural flavonoid derived from the root of liquorice, has been
reported to possess anti-inflammatory and antioxidant activities. Previous studies have …
reported to possess anti-inflammatory and antioxidant activities. Previous studies have …
Cellular and molecular insights into incomplete immune recovery in HIV/AIDS patients
L Yan, K Xu, Q Xiao, L Tuo, T Luo, S Wang… - Frontiers in …, 2023 - frontiersin.org
Highly active antiretroviral therapy (ART) can effectively inhibit virus replication and restore
immune function in most people living with human immunodeficiency virus (HIV). However …
immune function in most people living with human immunodeficiency virus (HIV). However …
Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV‐1 pathogenesis
Y Wang, L Lifshitz, NJ Silverstein, E Mintzer… - The EMBO …, 2023 - embopress.org
Innate lymphoid cells (ILCs) are a diverse population of cells that include NK cells and
contribute to tissue homeostasis and repair, inflammation, and provide protection from …
contribute to tissue homeostasis and repair, inflammation, and provide protection from …
Pro-tumorigenic and thrombotic activities of platelets in Lung Cancer
R Anderson, BL Rapoport, HC Steel… - International Journal of …, 2023 - mdpi.com
Aside from their key protective roles in hemostasis and innate immunity, platelets are now
recognized as having multifaceted, adverse roles in the pathogenesis, progression and …
recognized as having multifaceted, adverse roles in the pathogenesis, progression and …
Dapagliflozin attenuates myocardial fibrosis by inhibiting the TGF-β1/Smad signaling pathway in a normoglycemic rabbit model of chronic heart failure
X Chen, Q Yang, W Bai, W Yao, L Liu, Y Xing… - Frontiers in …, 2022 - frontiersin.org
Recent studies have shown that sodium-glucose cotransporter-2 (SGLT2) inhibitors play a
beneficial role for normoglycemic patients with heart failure (HF). However, the underlying …
beneficial role for normoglycemic patients with heart failure (HF). However, the underlying …
Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells
V Quagliariello, M Masarone, E Armenia… - Oncology …, 2019 - spandidos-publications.com
Butyric acid (BA) has been reported to induce anticancer effects on hepatocellular
carcinoma (HCC) cells both in vitro and in vivo. However, its delivery and release in cancer …
carcinoma (HCC) cells both in vitro and in vivo. However, its delivery and release in cancer …