[HTML][HTML] Machine learning predicts individual cancer patient responses to therapeutic drugs with high accuracy
C Huang, EA Clayton, LV Matyunina, LDE McDonald… - Scientific reports, 2018 - nature.com
Precision or personalized cancer medicine is a clinical approach that strives to customize
therapies based upon the genomic profiles of individual patient tumors. Machine learning …
therapies based upon the genomic profiles of individual patient tumors. Machine learning …
[HTML][HTML] Magnetic nanoparticles in theranostics of malignant melanoma
M Shevtsov, S Kaesler, C Posch, G Multhoff… - EJNMMI research, 2021 - Springer
Malignant melanoma is an aggressive tumor with a tendency to metastasize early and with
an increasing incidence worldwide. Although in early stage, melanoma is well treatable by …
an increasing incidence worldwide. Although in early stage, melanoma is well treatable by …
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient
PD-1-targeted therapy has dramatically changed advanced cancer treatment. However,
many questions remain, including specificity of T cells activated by PD-1 therapy and how …
many questions remain, including specificity of T cells activated by PD-1 therapy and how …
[HTML][HTML] Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors
SJ Dart, AM Cook, MJ Millward, AM McDonnell… - Scientific Reports, 2021 - nature.com
Advances in cancer immunology have increased the use of immune checkpoint inhibitors in
clinical practice, however not all patients respond, and treatment can have severe side …
clinical practice, however not all patients respond, and treatment can have severe side …
[HTML][HTML] Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma
Complex tumor microenvironmental (TME) features influence the outcome of cancer
immunotherapy (IO). Here we perform immunogenomic analyses on 67 intratumor sub …
immunotherapy (IO). Here we perform immunogenomic analyses on 67 intratumor sub …
A Fucose-Containing Sulfated Polysaccharide from Spatoglossum schröederi Potentially Targets Tumor Growth Rather Than Cytotoxicity: Distinguishing Action on …
MB Reis, AI Maximo, JM Magno, D de Lima Bellan… - Marine …, 2024 - Springer
Natural substances are strategic candidates for drug development in cancer research.
Marine-derived molecules are of special interest due to their wide range of biological …
Marine-derived molecules are of special interest due to their wide range of biological …
[HTML][HTML] IL-7 coupled with IL-12 increases intratumoral T cell clonality, leading to complete regression of non-immunogenic tumors
M Tasaki, M Yamashita, Y Arai, T Nakamura… - Cancer Immunology …, 2021 - Springer
Immune checkpoint inhibitors against PD-1, PD-L1 and CTLA-4 have altered the treatment
paradigm for various types of cancers in the past decade. However, they offer clinical …
paradigm for various types of cancers in the past decade. However, they offer clinical …
Superparamagnetic iron oxide nanoparticles induce persistent large foci of DNA damage in human melanoma cells post-irradiation
C Grissi, M Taverna Porro, M Perona, M Atia… - Radiation and …, 2023 - Springer
The synergy of superparamagnetic iron oxide nanoparticles (SPIONs) and ionizing radiation
(IR), attributed to reactive oxygen species (ROS) and DNA double-strand breaks (DSBs) …
(IR), attributed to reactive oxygen species (ROS) and DNA double-strand breaks (DSBs) …
Unveiling the Tumour Microenvironment: A Multi-Omics Machine Learning Approach for Personalised Cancer Treatment
K Tran - 2024 - eprints.qut.edu.au
Cancer is a complex and heterogeneous disease, which poses a challenge for precision
oncology. This thesis aims to advance precision oncology by improving treatment response …
oncology. This thesis aims to advance precision oncology by improving treatment response …
Magnetic nanoparticles in theranostics of malignant melanoma
S Maxim, S Kaesler, C Posch, M Gabriele… - EJNMMI …, 2021 - search.proquest.com
Malignant melanoma is an aggressive tumor with a tendency to metastasize early and with
an increasing incidence worldwide. Although in early stage, melanoma is well treatable by …
an increasing incidence worldwide. Although in early stage, melanoma is well treatable by …