Saffron bioactives crocin, crocetin and safranal: Effect on oxidative stress and mechanisms of action

D Cerdá-Bernad, E Valero-Cases… - Critical reviews in …, 2022 - Taylor & Francis
Saffron (Crocus sativus L.) is used as a spice for its organoleptic characteristics related to its
coloring and flavoring properties, and it has been also used in traditional medicine to treat …

A comprehensive review on biological activities and toxicology of crocetin

M Hashemi, H Hosseinzadeh - Food and Chemical Toxicology, 2019 - Elsevier
Natural products with high pharmacological potential and low toxicity have been considered
as the novel therapeutic agents. Crocetin is an active constituent of saffron (Crocus sativus …

A review of the use of antioxidants in bovine sperm preparation protocols

V Sapanidou, MP Tsantarliotou… - Animal Reproduction …, 2023 - Elsevier
Reactive oxygen species (ROS) and oxidative stress (OS), the imbalance between the
production of free radicals and the cellular antioxidant defenses, are discussed in relation to …

The natural carotenoid crocetin and the synthetic tellurium compound AS101 protect the ovary against cyclophosphamide by modulating SIRT1 and mitochondrial …

G Di Emidio, G Rossi, I Bonomo… - Oxidative medicine …, 2017 - Wiley Online Library
Cancer therapies are associated with increased infertility risk due to accelerated
reproductive aging. Oxidative stress (OS) is a potential mechanism behind ovarian toxicity …

Melatonin protects bovine spermatozoa by reinforcing their antioxidant defenses

SN Lavrentiadou, V Sapanidou, EE Tzekaki… - Animals, 2023 - mdpi.com
Simple Summary In bovine reproduction, genetically superior semen is customarily frozen to
ensure its conservation and broad use. Freezing/thawing and handling compromise the …

In vitro effects of Capparis spinosa L. extract on human sperm function, DNA fragmentation, and oxidative stress

MK Rad, A Ghani, E Ghani - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Oxidative stress is one of the underlying causes of male
infertility. Medicinal plants have many benefits for infertility treatment in men. Aim of the study …

Effects of vitamin D supplementation in extender on sperm kinematics and apoptosis following the freeze-thaw process in normozoospermic and asthenozoospermic …

R Asadpour, M Taravat, M Rahbar… - Basic and Clinical …, 2021 - Springer
Background Asthenozoospermia is a usual male infertility factor, characterized by
decreased semen quality. It has been revealed that antioxidants improve sperm function …

Effect of astaxanthin in extenders on sperm quality and functional variables of frozen-thawed boar semen

A Basioura, IA Tsakmakidis, EA Martinez, J Roca… - Animal reproduction …, 2020 - Elsevier
The aim of the study was to determine whether the presence of astaxanthin (ASX) protects
boar spermatozoa against damage related to cryopreservation. Pooled ejaculates extended …

Astaxanthin Improved the Quality of Hu Ram Semen by Increasing the Antioxidant Capacity and Mitochondrial Potential and Mitigating Free Radicals-Induced …

T Sohail, L Zhang, X Wang, C Jiang, J Wang, X Sun… - Animals, 2024 - mdpi.com
Simple Summary Sheep's sperm is very sensitive to free radical-mediated oxidative and per
oxidative damage during preservation at 4° C, leading to deterioration in semen quality. The …

Adverse effects of in vitro manipulation of spermatozoa

E Baldi, L Tamburrino, M Muratori… - Animal reproduction …, 2020 - Elsevier
Abstract Development of in vitro reproduction techniques has not only offered some infertile
couples the possibility to have a child, it also revolutionized animal reproduction. Although in …