Obesity is an important cause of morbidity and mortality in developed countries, and is also
becoming increasingly prevalent in the developing world. Although environmental factors …

A diet enriched in PUFAs, in particular of the n-3 family, decreases adipose tissue mass and
suppresses development of obesity in rodents. Although several nuclear hormone receptors …

To pursue a systematic approach to the discovery of functional connections among
diseases, genetic perturbation, and drug action, we have created the first installment of a …

Background Obesity has become a leading global health problem owing to its strong
association with a high incidence of diseases. Aim To induce rat obesity using high fat diet …

Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic
steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons. In this …

Objective: To assess the effects of high‐fat feeding on white adipose tissue gene expression
and liver oxidative stress. Research Methods and Procedures: Male Wistar rats were fed on …

To understand the molecular mechanisms underlying alterations in the pathophysiologic
status of dietary obesity, we examined hepatic genes differentially expressed in a long-term …

n-3 PUFA have shown potential anti-obesity and insulin-sensitising properties. However, the
mechanisms involved are not clearly established. The aim of the present study was to …

The quest for effective strategies to treat obesity has propelled fat research into an
exploration of the molecular processes that drive adipocyte formation, and hence body fat …

Obesity originates from a failure of the body-weight control systems, which may be affected
by changing environmental influences. Basically, the obesity risk depends on two important …