Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome
E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
Key signalling pathways underlying the aetiology of polycystic ovary syndrome
KA Walters, A Moreno-Asso, NK Stepto… - Journal of …, 2022 - joe.bioscientifica.com
Polycystic ovary syndrome (PCOS) is a common endocrine condition characterised by a
range of reproductive, endocrine, metabolic and psychological abnormalities. Reports …
range of reproductive, endocrine, metabolic and psychological abnormalities. Reports …
Androgen action in adipose tissue and the brain are key mediators in the development of PCOS traits in a mouse model
MJ Cox, MC Edwards, V Rodriguez Paris… - …, 2020 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a complex disorder characterized by endocrine,
reproductive, and metabolic abnormalities. Despite PCOS being the most common …
reproductive, and metabolic abnormalities. Despite PCOS being the most common …
[HTML][HTML] Androgen-induced insulin resistance is ameliorated by deletion of hepatic androgen receptor in females
S Andrisse, M Feng, Z Wang, O Awe, L Yu… - … : official publication of …, 2021 - ncbi.nlm.nih.gov
Androgen excess is one of the most common endocrine disorders of reproductive-aged
women, affecting up to 20% of this population. Women with elevated androgens often exhibit …
women, affecting up to 20% of this population. Women with elevated androgens often exhibit …
Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model
T Xiong, V Rodriguez Paris… - American Journal …, 2022 - journals.physiology.org
Polycystic ovary syndrome (PCOS) is a common, multifactorial disorder characterized by
endocrine, reproductive, and metabolic dysfunction. As the etiology of PCOS is unknown …
endocrine, reproductive, and metabolic dysfunction. As the etiology of PCOS is unknown …
Androgen inhibition of reproductive neuroendocrine function in females and transgender males
AS Kauffman - Endocrinology, 2024 - academic.oup.com
Ovarian function is controlled by pituitary secretion of luteinizing hormone (LH) and follicle
stimulating hormone (FSH), which in turn are governed by gonadotropin releasing hormone …
stimulating hormone (FSH), which in turn are governed by gonadotropin releasing hormone …
Reproductive Profile of Neuronal Androgen Receptor Knockout Female Mice With a Low Dose of DHT
V Ubba, S Joseph, O Awe, D Jones, MK Dsilva… - …, 2024 - academic.oup.com
Hyperandrogenism and polycystic ovarian syndrome result from the imbalance or increase
of androgen levels in females. Androgen receptor (AR) mediates the effects of androgens …
of androgen levels in females. Androgen receptor (AR) mediates the effects of androgens …
An improved time-and labor-efficient protocol for mouse primary hepatocyte isolation
Primary hepatocytes are used extensively in liver in vitro research, especially in glucose
metabolism studies. A base technique has been adapted based on different needs, like time …
metabolism studies. A base technique has been adapted based on different needs, like time …
Comparison of reproductive function between normal and hyperandrogenemia conditions in female mice with deletion of hepatic androgen receptor
Obesity, altered glucose homeostasis, hyperinsulinism, and reproductive dysfunction
develops in female humans and mammals with hyperandrogenism. We previously reported …
develops in female humans and mammals with hyperandrogenism. We previously reported …
Lower FSH with normal fertility in Male mice lacking gonadotroph kisspeptin receptor
Y Ma, O Awe, S Radovick, X Yang, S Divall… - Frontiers in …, 2022 - frontiersin.org
The kisspeptin receptor, crucial for hypothalamic control of puberty and reproduction, is also
present in the pituitary gland. Its role in the pituitary gland is not defined. Kisspeptin …
present in the pituitary gland. Its role in the pituitary gland is not defined. Kisspeptin …