Diagnosis and treatment of primary aldosteronism: practical clinical perspectives

WF Young Jr - Journal of internal medicine, 2019 - Wiley Online Library
Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021

M Naruse, T Katabami, H Shibata, M Sone… - Endocrine …, 2022 - jstage.jst.go.jp
Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality
rates than essential hypertension. The Japan Endocrine Society (JES) has developed an …

Diagnosis and management of primary hyperaldosteronism in patients with hypertension: a practical approach endorsed by the British and Irish Hypertension Society

L Faconti, S Kulkarni, C Delles, V Kapil… - Journal of Human …, 2024 - nature.com
Alongside the lack of homogeneity among international guidelines and consensus
documents on primary hyperaldosteronism, the National UK guidelines on hypertension do …

Clinical outcomes after unilateral adrenalectomy for primary aldosteronism

WMCM Vorselaars, S Nell, EL Postma… - JAMA …, 2019 - jamanetwork.com
Importance In addition to biochemical cure, clinical benefits after surgery for primary
aldosteronism depend on the magnitude of decrease in blood pressure (BP) and use of …

Primary aldosteronism: a common cause of resistant hypertension

GA Kline, APH Prebtani, AA Leung, EL Schiffrin - Cmaj, 2017 - Can Med Assoc
• Patients who cannot be considered for adrenalectomy may consider an empiric trial of
spironolactone or eplerenone for blood pressure control.• If a normal or negative result for …

Adrenal venous sampling–guided adrenalectomy rates in primary aldosteronism: results of an international cohort (AVSTAT)

Y Ohno, M Naruse, F Beuschlein… - The Journal of …, 2021 - academic.oup.com
Context Adrenal venous sampling (AVS) is the current criterion standard lateralization
technique in primary aldosteronism (PA). Japanese registry data found that 30% of patients …

Predictors of clinical success after surgery for primary aldosteronism in the Japanese nationwide cohort

M Morisaki, I Kurihara, H Itoh, M Naruse… - Journal of the …, 2019 - academic.oup.com
Context Aldosterone-producing adenomas are a curable subtype of primary aldosteronism
(PA); however, hypertension persists in some patients after adrenalectomy. Objective To …

Evolution of the cardiometabolic profile of primary hyperaldosteronism patients treated with adrenalectomy and with mineralocorticoid receptor antagonists: results …

M Araujo-Castro, M Paja Fano, M González Boillos… - Endocrine, 2022 - Springer
Objective To analyze the evolution of the cardiometabolic profile of patients with primary
hyperaldosteronism (PA) after the treatment with surgery and with mineralocorticoid receptor …

Urine steroid profile as a new promising tool for the evaluation of adrenal tumors. Literature review

M Araujo-Castro, P Valderrábano… - Endocrine, 2021 - Springer
Purpose To review the literature assessing the diagnostic performance of urinary steroid
profiling (USP) by high-performance liquid chromatography (LC–MS) or gas …

Discordance between imaging and adrenal vein sampling in primary aldosteronism irrespective of interpretation criteria

D Sam, GA Kline, B So, AA Leung - The Journal of Clinical …, 2019 - academic.oup.com
Background Subtyping of primary aldosteronism (PA) using imaging and adrenal vein
sampling (AVS) may yield discordant results, causing confusion in management …