MicroRNAs (miRNAs) are short single-stranded non-coding RNA sequences that
posttranscriptionally regulate up to 60% of protein encoding genes. Evidence is emerging …

Introduction Human brucellosis is a zoonotic bacterial disease with up to 500,000 new cases
each year. The major evasion mechanisms from the host immune system by Brucella are …

Brucellosis, caused by a number of Brucella species, remains the most prevalent zoonotic
disease worldwide. Brucella establish chronic infections within host macrophages despite …

Objectives The underlying mechanism of the inflammatory response against Brucellosis
caused by Brucella remains poorly understood. This study aimed to determine the role of …

Simple Summary This study was conducted to comprehensively understand the functional
mechanisms of CD8+/− porcine gamma delta (γδ) T cells related to the immune system …

Brucellosis is a serious infectious disease that continues to be a significant cause of
morbidity worldwide and across all ages. Despite early diagnosis and treatment, 10–30% of …

Hepatitis B infection caused by the hepatitis B virus is a life-threatening cause of liver
fibrosis, cirrhosis, and hepatocellular carcinoma. Researchers have produced multiple in …

The secretion of interleukin (IL)-1 family cytokines is one of the most potent and earliest pro-
inflammatory responses triggered by brucellosis. However, the roles of the most recently …

Long non-coding RNAs (LncRNAs) are significant contributors to bacterial infections and
host defense responses, presenting a novel class of gene regulators beyond conventional …

Innate recognition of Brucella spp. is a key step in the activation of inflammation. CD14 binds
PAMPs and is involved in LPS-induced pro-inFammatory cytokine release. Previously we …