[HTML][HTML] Signaling pathways and targeted therapy for myocardial infarction
Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
Basic and Translational Research in Cardiac Repair and Regeneration: JACC State-of-the-Art Review
This paper aims to provide an important update on the recent preclinical and clinical trials
using cell therapy strategies and engineered heart tissues for the treatment of postinfarction …
using cell therapy strategies and engineered heart tissues for the treatment of postinfarction …
All roads lead to Rome (the heart): cell retention and outcomes from various delivery routes of cell therapy products to the heart
In the past decades, numerous preclinical studies and several clinical trials have evidenced
the feasibility of cell transplantation in treating heart diseases. Over the years, different …
the feasibility of cell transplantation in treating heart diseases. Over the years, different …
[HTML][HTML] Human stem cells for cardiac disease modeling and preclinical and clinical applications—are we on the road to success?
CD Correia, A Ferreira, MT Fernandes, BM Silva… - Cells, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO)
as the leading cause of death, contributing to a significant and growing global health and …
as the leading cause of death, contributing to a significant and growing global health and …
[HTML][HTML] Therapies to prevent post-infarction remodelling: From repair to regeneration
P Contessotto, A Pandit - Biomaterials, 2021 - Elsevier
Myocardial infarction is the first cause of worldwide mortality, with an increasing incidence
also reported in developing countries. Over the past decades, preclinical research and …
also reported in developing countries. Over the past decades, preclinical research and …
Exosome-bearing hydrogels and cardiac tissue regeneration
H Amini, AR Namjoo, MT Narmi, N Mardi… - Biomaterials …, 2023 - spj.science.org
Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …
has become the predominant cause of human disability and mortality in the clinical setting …
[HTML][HTML] Myocardial regeneration protocols towards the routine clinical scenario: An unseemly path from bench to bedside
Heart failure secondary to cardiomyocyte loss and/or dysfunction is the number one killer
worldwide. The field of myocardial regeneration with its far-reaching primary goal of cardiac …
worldwide. The field of myocardial regeneration with its far-reaching primary goal of cardiac …
Function follows form―a review of cardiac cell therapy―
K Nakamura, CE Murry - Circulation Journal, 2019 - jstage.jst.go.jp
The investment of nearly 2 decades of clinical investigation into cardiac cell therapy has yet
to change cardiovascular practice. Recent insights into the mechanism of cardiac …
to change cardiovascular practice. Recent insights into the mechanism of cardiac …
Danish phase II trial using adipose tissue derived mesenchymal stromal cells for patients with ischaemic heart failure
AA Qayyum, M Mouridsen, B Nilsson… - ESC Heart …, 2023 - Wiley Online Library
Aims Patients suffering from chronic ischaemic heart failure with reduced left ventricular
ejection fraction (HFrEF) have reduced quality‐of‐life, repetitive hospital admissions, and …
ejection fraction (HFrEF) have reduced quality‐of‐life, repetitive hospital admissions, and …
[HTML][HTML] Neovascularization: the main mechanism of MSCs in ischemic heart disease therapy
W Shi, Q Xin, R Yuan, Y Yuan, W Cong… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cell (MSC) transplantation after myocardial infarction (MI) has been
shown to effectively limit the infarct area in numerous clinical and preclinical studies …
shown to effectively limit the infarct area in numerous clinical and preclinical studies …